Intraoral soft tissue lipomas: clinicopathological features from 91 cases diagnosed in a single Oral Pathology service

Abstract

Background intraoral soft tissue lipomas are relatively uncommon mesenchymal neoplasms. Few papers have been published comparing the clinicopathological features of these tumors in different populations. The aim of the present study was to analyze the clinicopathological features from intraoral soft tissue lipomas diagnosed in a Brazilian population. Material and Methods all cases diagnosed as intraoral soft tissue lipomas in an Oral Pathology laboratory from 2005 to 2019 were retrieved and descriptively analyzed; statistical analysis was performed for comparison of the clinical and demographic parameters. Results 91 intraoral lipomas were retrieved, including 56 lipomas, 30 fibrolipomas, 2 spindle cell lipomas, 2 angiolipomas, and 1 chondrolipoma. Mean age of the patients was 62.2 years and females represented 57.1% of the sample. Mean time of complaint was 45.4 months and mean size of the lesions was 16.2 millimeters. Buccal mucosa (38.8%), lower lip (18.8%) and tongue (16.5%) were the most commonly affected locations. Fibrolipomas were more common in females ( p =0,037) and presented as smaller lesions ( p =0,011) in comparison to lipomas. Conclusions report of clinicopathological data from intraoral lipomas aid in establishing their differential diagnostic criteria and clinical profile in this specific location. Key words: Lipoma, fibrolipoma, oral, mouth, spindle cell lipoma, angiolipoma, chondrolipoma.

Oral Lipoma: A Case Report

“…Lipomas are described by a proliferation of mature adipocytes with different amounts of connective tissue, which consists of bundles of collagen fibers and blood vessels [15]. Each lipoma is generally encompassed by a fibrous capsule, permitting an increase in adipocytes to be observed with a well-defined border [16].…”

Lipoma de piso de boca. Presentación atípica

“…El término «lipoma» comprende varias entidades diferentes, incluido el lipoma convencional y varios otros subtipos histológicos con diferentes características clínicas e histológicas, tales como: fibrolipoma, lipoma mixoide, angiolipoma, miolipoma, lipoma de células fusiformes/lipoma pleomórfico, infiltrante (intramuscular) lipoma, lipoma intermuscular, hibernoma, lipomatosis, lipoblastoma/lipoblastomatosis, lipomas de las glándulas salivales (sialolipomas), lipomas atípicos (tumores lipomatosos atípicos), osteolipoma, condrolipoma, angiomiolipoma, mielolipoma y lipoma condroide. 1 La mayoría de estos subtipos han sido descritos y estudiados en tejido subcutáneo y otras regiones anatómicas, y existe poca información sobre la frecuencia y las características clínico-patológicas de estas variantes histológicas en la cavidad oral.…”

“…Alrededor de 15 a 20% de todos los lipomas afectan la región de cabeza y cuello, y se estima que sólo de 1 a 4% de estos afectan la cavidad bucal, donde representan de 0.1 a 5% de todos los tumores benignos. 1…”

Oral lipoma: A case report with comprehensive ultrasonographic features and treatment plan

“…About 15% to 20% of all lipomas manifest in the head and neck region. 4 The diagnosis of lipomas in the head and neck region benefits greatly from imaging. Ultrasonography is the first method of choice for identifying these soft-tissue growths since it is the most affordable, widely available, very sensitive, highly selective, and able to provide focused, real-time evaluation of the lesion of interest.…”