Intraoral spindle cell lipoma: Case report with correlated light and electron microscopy

McDaniel, Raymond K.; Newland, J R; Chiles, D.G.

doi:10.1016/0030-4220(84)90260-3

Cited by 57 publications

(20 citation statements)

References 8 publications

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“…Spindle cell lipomas are infrequently encountered in the oral region, with lingual examples of this entity in particular being distinctly rare. To our knowledge, only 24 cases of spindle cell lipoma involving the tongue have been reported in the English literature [3,5,[9][10][11][12][13][14][15][16][17][18][19][20][21]. The clinical and pathologic features of lingual spindle cell lipoma based on findings from the present series combined with previously published data are summarized in Table 3.…”

Section: Discussionmentioning

confidence: 83%

“…While most ordinary lipomas of the oral cavity involve the buccal mucosa, tongue or lip [1][2][3][4][5][6][7][8], lingual examples of spindle cell lipoma remain rare. The reported literature pertaining to spindle cell lipoma of the tongue is relatively sparse and comprised predominantly of single case reports and limited descriptions of small numbers of cases among larger series of lipomas of the oral cavity [3,5,[9][10][11][12][13][14][15][16][17][18][19][20][21]. In this study, we analyzed eight new cases of lingual spindle cell lipoma in order to further characterize the clinicopathologic features of this uncommon type of intraoral lipomatous tumor.…”

Section: Introductionmentioning

confidence: 99%

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Spindle Cell Lipoma of the Tongue: A Clinicopathologic Study of 8 Cases and Review of the Literature

Lau

Bishop

Thompson

2014

Head and Neck Pathol

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Spindle cell lipoma is a histologically distinct variant of lipoma characteristically arising in the subcutis of the posterior neck, upper back, or shoulder. Spindle cell lipomas infrequently occur within the oral cavity and, in particular, rarely involve the tongue. The clinical and pathologic features of eight cases of spindle cell lipoma affecting the tongue were analyzed. The study group included five men and three women ranging in age from 35 to 80 years (mean 57.4 years). Most lesions presented as either a painless or slowly growing lingual mass. The tumors were well circumscribed and characterized microscopically by a mixture of mature adipocytes, cytologically bland spindle cells, and interspersed bundles of thick collagen fibers in variable proportions. Myxoid stroma was a prominent feature in three lesions. The spindle cells were positive with CD34, while negative with S-100 protein, desmin, and smooth muscle actin. Treatment consisted of local excision in all cases. There have been no recurrences to date, with clinical follow up information available for all patients (range 11-118 months; mean 50.8 months). Lingual examples of spindle cell lipoma should be distinguished from other fat containing spindle cell neoplasms that can arise at this anatomic site.

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Section: Discussionmentioning

confidence: 83%

Section: Introductionmentioning

confidence: 99%

Spindle Cell Lipoma of the Tongue: A Clinicopathologic Study of 8 Cases and Review of the Literature

Lau

Bishop

Thompson

2014

Head and Neck Pathol

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“…One important aspect reported in the study of Furlong et al [3] was the reclassiWcation of 11 cases of spindle cell lipomas previously diagnosed as myxoid lipomas. Billings et al [40] pointed out that prior to the Wrst report of spindle cell lipoma of the oral cavity [45], cases of this variant may have been described in the literature under the designation of Wbrolipoma or myxoid lipoma. These observations emphasize the importance of immunohistochemical analysis using anti-CD34 antibody [13,40] in cases of lipomas that present myxoid areas associated with a spindle cell component.…”

Section: Discussionmentioning

confidence: 99%

Lipomas of the oral cavity: clinical and histopathologic study of 41 cases in a Brazilian population

Juliasse

Nonaka

Pinto

et al. 2009

Eur Arch Otorhinolaryngol

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This study evaluated the clinical and histopathologic aspects of 41 cases of oral lipomas diagnosed in a Brazilian population. All records from patients diagnosed with oral lipoma between 1970 and 2008 were reviewed. Histological sections were evaluated by light microscopy. There was a predominance of females (2.4:1), with a peak incidence between the sixth and seventh decade. The buccal mucosa was the most aVected site (53.7%), followed by the buccal sulcus (14.6%) and tongue (9.8%). Tumor size ranged from 0.5 to 10 cm and the mean reported duration was 48 months. Histologically, the following variants were identiWed: lipoma (41.5%), Wbrolipoma (34.1%), spindle cell lipoma (9.8%), sialolipoma (9.8%), osteolipoma (2.4%), and chondrolipoma (2.4%). Most tumors were well delimited, irrespective of the variant. Lipomas are rare tumors of the oral cavity. The characterization of new variants, such as sialolipomas, and the identiWcation of histological subtypes in already known variants, such as low-fat and fat-free spindle cell lipomas, highlight the importance for careful microscopic evaluation of these tumors, which might be combined with immunohistochemistry in some cases.

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“…[7][8][9][10] There are also a few reports that included electron microscopic and cytogenetic findings of SCL. 8,[11][12][13] The cytologic features of SCL, however, are poorly defined, with only three patients described in the literature. 14 -16 In addition, there are two series of FNA in patients with soft tissue lesions that mention SCLs, but without providing any further descriptions of their cytology.…”

mentioning

confidence: 99%

Distinct cytologic features of spindle cell lipoma

Domanski

Carlén

Jonsson

et al. 2001

Cancer

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Intraoral spindle cell lipoma: Case report with correlated light and electron microscopy

Cited by 57 publications

References 8 publications

Spindle Cell Lipoma of the Tongue: A Clinicopathologic Study of 8 Cases and Review of the Literature

Spindle Cell Lipoma of the Tongue: A Clinicopathologic Study of 8 Cases and Review of the Literature

Lipomas of the oral cavity: clinical and histopathologic study of 41 cases in a Brazilian population

Distinct cytologic features of spindle cell lipoma

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