Intraosseous jaw lesions

Abstract

Context: Jaw bones can be afflicted by to a diverse group of lesions ranging from developmental, reactive/inflammatory, cystic lesions to tumors and tumor-like lesions Objectives: The objective of this study is to determine the relative frequency, demographic and pathologic profiles of patients with intraosseous jaw lesions from Thailand. Subjects and Methods: Biopsy records from 1995 to 2019 were reviewed. Age, gender and location of the lesions were collected from the biopsy records. Data were analyzed by appropriate statistics using the IBM SPSS software version 22.0. Results: From 23,344 accessioned cases, 7382 cases (31.62%) were encountered within the jaw bones. Age of the participants ranged from 1 to 96 years with the mean ± standard deviation = 36.05 ± 17.80 years. Pediatric participants (aged ≤16 years) comprised 13.80% of all the participants, whereas the geriatric ones (aged ≥65 years) accounted for 7.55%. The male-to-female ratio was 0.89:1. The majority of lesions were observed in the mandible. The most prevalent intra-osseous jaw lesion was radicular cyst followed by dentigerous cyst and ameloblastoma. The most common malignant tumor was osteosarcoma followed by ameloblastic carcinoma and lymphoma. Among the pediatric participants, dentigerous cyst was the most prevalent jaw lesion, while that in the geriatric participants was radicular cyst. Conclusions: This is the largest study on intra-osseous jaw lesions encompassing several pathological entities ever conducted from Thailand. It thus provides an invaluable database for clinicians to formulate a differential diagnosis as well as for the pathologists to render the final diagnosis. The results of this study are in accordance with previous studies in general.

Cysts of the jaws: A multicentre study

“…In overall, male patients with CsOJ outnumbered their female counterpart as in previous studies (Aquilanti et al, 2021; Butt et al, 2011; Del Corso et al, 2014; Grossmann et al, 2007; Jaeger et al, 2017; Johnson et al, 2013; Jones et al, 2006; Kambalimath et al, 2014; Kammer et al, 2020; Lo Muzio et al, 2017; Mosqueda‐Taylor et al, 2002; Ochsenius et al, 2007; Tamiolakis et al, 2019; Tekkesin et al, 2012; Tortorici et al, 2008), especially studies from Southeast Asia and the Middle East and North America (Dhanuthai et al, 2022; Sharifian & Khalili, 2011; Zhang et al, 2010) except in the study by de Souza et al (2010) in which the reverse was true. Moreover, OCs, NOCs as well as Cysts not otherwise specified all consistently demonstrated a male predilection.…”

A case of giant ameloblastoma: destructive effect on the facial skeleton and soft tissues of the head and neck

“…4 Most cases of odontogenic tumors are diagnosed in young adults, with a median age of 10 to 38 years, with no significant sex predilection. [5][6][7][8] In Asia and North America, the mean (AE standard deviation) age of patients with ameloblastoma is 38.27 AE 17.78 years. 6 More specifically, in the Thai population, Kitisubkanchana et al reported an average age of 34.9 years; 7 Soylu et al reported an average age of 39.35 years in Turkey (Middle Anatolia); 8 and older sources report a mean of 36 years.…”

“…[5][6][7][8] In Asia and North America, the mean (AE standard deviation) age of patients with ameloblastoma is 38.27 AE 17.78 years. 6 More specifically, in the Thai population, Kitisubkanchana et al reported an average age of 34.9 years; 7 Soylu et al reported an average age of 39.35 years in Turkey (Middle Anatolia); 8 and older sources report a mean of 36 years. 5 Approximately 80% of ameloblastomas occur in the mandible, usually in the posterior region, and represent only 1% of all oral/head and neck tumors.…”