Intrapartum amnioinfusion for meconium‐stained amniotic fluid: a systematic review of randomised controlled trials

Jana, Narayan; Barik, Shreya; Nk, Arora

doi:10.1111/j.1471-0528.2007.01536.x

Cited by 2 publications

(4 citation statements)

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“…The current consensus is that in clinical settings with standard perinatal surveillance, evidence does not support the use of amnioinfusion for MSAF. However, when there is limited perinatal surveillance, where complications of MSAF are common, it appears to reduce the incidence of MAS [11,12].…”

Section: Obstetrical Managementmentioning

confidence: 99%

Meconium Aspiration Syndrome: An Insight

Raju

Sondhi

2010

Medical Journal Armed Forces India

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Meconium aspiration syndrome (MAS) is respiratory distress in a newborn baby caused by the presence of meconium in the tracheobronchial airways. The aspiration of meconium stained amniotic fluid by the fetus can happen during antepartum or intrapartum periods and can result in airway obstruction, interference with alveolar gas exchange, chemical pneumonitis as well as surfactant dysfunction. These pulmonary effects cause gross ventilation-perfusion mismatching. To complicate matters further, many infants with MAS have primary or secondary persistent pulmonary hypertension of the newborn as a result of chronic in utero stress and thickening of the pulmonary vessels. Although meconium is sterile, its presence in the air passages can predispose the infant to pulmonary infection. MAS is essentially a clinical diagnosis and should always be suspected in a child with respiratory distress and meconium-stained amniotic fluid at delivery. Though a known entity for a long time, its management still remains contentious. Intubation and direct tracheal suction is performed when meconium is observed in the amniotic fluid and the infant is not vigorous. Subsequent management involves ventilation, surfactant instillation and lavage, inhaled nitric oxide and high frequency ventilation. The role of steroids continues to be controversial.

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Section: Obstetrical Managementmentioning

confidence: 99%

Meconium Aspiration Syndrome: An Insight

Raju

Sondhi

2010

Medical Journal Armed Forces India

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“…Sir, First, we would like to thank Jana et al for their valuable comments on our paper Intrapartum amnioinfusion for meconium-stained amniotic fluid: a systematic review of randomised controlled trials. 1,2 We agree that electronic fetal monitoring may not be the only essential component of standard care. We believe that fetal scalp blood sampling can be a useful adjunct to electronic fetal monitoring.…”

mentioning

confidence: 93%

“…1,2 We agree that electronic fetal monitoring may not be the only essential component of standard care. We believe that fetal scalp blood sampling can be a useful adjunct to electronic fetal monitoring.…”

mentioning

confidence: 99%

“…Jana et al have suggested that gestational age, birthweight, or presence or absence of intrauterine growth restriction could be variables of interest for stratified analyses. 1 To be useful in clinical practice, only variables that are available in labour should be used as stratifying variables, as variables such as birthweight are only determined after labour. However, in meta-analyses, such stratification requires the use of individual patient data, which may be difficult to obtain.…”

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confidence: 99%

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