“…Hereditary paragangliomas (PGL) have also been associated with germline mutations of the genes that encode three of the four subunits of mitochondrial complex II, succinate dehydrogenase (SDH) B, C, and D. 1 When such tumours occur in extra-adrenal sites, their diagnosis can be challenging; for example, to date there are only three reported cases of intrarenal pheochromocytoma. [2][3][4] We conducted a study of gene expression profiles of kidney tumours using a cDNA microarray technique. These gene expression profiles can serve as the molecular signatures of particular tumours, and different groups of genes may correlate with the behaviour of the tumours (for example, invasiveness, angiogenesis), clinical outcome, and drug response.…”