Intraretinal recording with micropipette electrodes in the intact cat eye

Receptive fields of ganglion cells in the cat's retina

“…Micropipettes recorded this activity within the retina at depths up to 30-40, (Brown & Wiesel, 1959), whereas platinum electrodes only recorded from the surface of the retina. Cells were continuously active during steady background illumination; this maintained activity showed great variation from unit to unit (Kuffler, FitzHugh & Barlow, 1957).…”

“…A detailed description of the method used in these experiments has recently been given (Brown & Wiesel, 1959). Twenty-six catswere kept underlight anaesthesiawithintraperitoneal injections of sodium pentobarbital (initial dose 20-30 mg/kg) and Dial (allobarbitone; Ciba) 584 T. WIESEL with urethane (initial dose 0-25 ml./kg).…”

Cross‐correlation analysis of the maintained discharge of rabbit retinal ganglion cells.

“…A specially designed electrode holder and manipulator apparatus, similar to that used by others (Brown & Wiesel, 1959: Steinberg, Walker & Johnson, 1968, was then positioned. An 18 gauge syringe needle was inserted through the sclera just behind the limbus and served as a guide tube for micro-electrodes passing through it.…”

Localization of electrical activity in the cat retina by an electrode marking method

“…Although refinements have improved this technique (Tomita & Torihama, 1956;Brown & Wiesel, 1959), the method at best seems unreliable because of inability to control the angle of the electrode path after it has entered the retina. Thus a number of authors have introduced staining material into the retina from-the electrode tip and recovered the stain spots in histological sections (MacNichol & Svaetichin, 1958; Mitarai, 1958Mitarai, , 1960Oikawa, Ogawa & Motokawa, 1959; Tomita, Murakami, Sato & Hashimoto, 1959;Gouras, 1960).…”