Intraspecific Variability of the Essential Oil of <i>Ziziphora clinopodioides</i> ssp. <i>rigida</i> from Iran

Sonboli, Ali; Atri, Morteza; Shafiei, Sedighe

doi:10.1002/cbdv.200900336

Cited by 29 publications

(23 citation statements)

References 16 publications

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“…Caffeic acid (17) Z. clinopodioides [80] Anticancer potential reviewed [98] Protection of endothelial cells (review by Fuentes and Palomo [99]) General review on applications [100] O H O OH Ethyl ester of caffeic acid (18) Z. clinopodioides [4] Weak inhibitory activity on NO production stimulated by LPS and IFN-γ in RAW 264.7 cells [4] Antihypertensive [101,102] Anti-inflammatory [103][104][105] Antidiabetic [106] Inhibitory activity against amyloidogenesis [107] Antioxidative [108][109][110][111] Anticancer [112] O H…”

Section: O-glc Hmentioning

confidence: 99%

“…Some relatively uncommon fatty acid-substituted flavones ziziphorin A and B (9 and 10) were isolated from Z. tenuior [38]. Furthermore, several phenolic acids and their esters, like caffeic acid (17) and its ethyl ester (18) and rosmarinic acid (19), salicylic acid (20) and benzoic acid (21), and derivatives of benzyl alcohol were detected in Ziziphora species (Table 1). The bioactivity of Ziziphora flavonoids was studied for several single compounds; therefore, we will mention the activities in connection to possible Ziziphora use.…”

Section: Omementioning

confidence: 99%

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Kazakh Ziziphora Species as Sources of Bioactive Substances

et al. 2016

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Ziziphora species represent the prototypical example of the Lamiaceae family. The phytochemicals present in Ziziphora include monoterpenic essential oils, triterpenes and phenolic substances belonging to the flavonoids. In Kazakh traditional medicine, Ziziphora species possess several medicinal uses. In particular, Z. bungeana Lam. and Z. clinopodioides Lam. are used for the treatment of illnesses related to the cardiovascular system or to combat different infections. Unfortunately, the majority of the information about the complex Ziziphora species is only available in Russian and Chinese language, therefore, we decided gather all available information on Kazakhstan Ziziphora, namely its content compounds, medicinal uses and published patents, to draw the attention of scientists to this very interesting plant with high medicinal potential.

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Section: O-glc Hmentioning

confidence: 99%

Section: Omementioning

confidence: 99%

Kazakh Ziziphora Species as Sources of Bioactive Substances

et al. 2016

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“…As mentioned above, numerous reports could be found in the literature in which the most frequency in all of the chemical profiles is related to oxygenated monoterpenes like pulegone and piperitenone 3,[60][61][62][63][64][65] with the exception of one report as an improved GC-MS analysis using multivariate curve resolution approach in which pulegone (38.3%), isomenthone (7.06%), limonene (2.59%) along with some unusual compounds involving 3',5'-dihydroxyacetophenone (22.83%), 2-methyl-5-(1-methylethyl)-phenol (3.41%) and 2-acetyl-4,4-dimethyl-cyclopent-2-enone (2.49%) constitute major natural compounds in the oil 61 .These findings altogether denote that the essential oils from different organs of various species of Ziziphora plants could be considered as potential sources of pulegone.…”

Section: Fig 1: the Gc-ms Chromatogram Related To Volatile Profiles mentioning

confidence: 99%

Gas Chromatographic-Mass Spectrometric Analysis of Volatiles Obtained by HS-SPME-GC-MS Technique from Aerial Parts of Ziziphora Capitata L., and Evaluation for Biological Activity.

Mohammadhosseini¹,

Akbarzadeh²,

Hashemi‐Moghaddam³

et al. 2016

Orient. J. Chem

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Volatile constituent components from aerial parts of Ziziphora capitata L. were successfully separated using headspace solid-phase microextraction (HS-SPME) approach, and were subsequently analyzed by means of GC and GC-MS instruments. The major volatile compounds were found to be pulegone (23.8%), p-mentha-3,8-diene (17.0%), a-pinene (11.4%), b-pinene (11.3%) and p-menth-3-en-8-ol (8.3%) altogether involving more than 70% of the profile accounting for high frequency of monoterpene hydrocarbons. Moreover, the methanolic extracts of Z. capitata were evaluated for possible antioxidant and antibacterial activities. In this regard, antioxidant activity of the extracts was determined by monitoring the scavenging capability of the DPPH free radical. Antibacterial activity was evaluated against some of Gram-positive and Gram-negative bacteria using disc diffusion and broth microdilution methods. The minimum inhibitory concentration (MIC) and minimal bactericidal concentration (MBC) values varied over the ranges 3.12-12.5 mg/ml and 6.25-25 mg/ml, respectively. Our study revealed that methanolic extracts of Z. capitata exhibit strong and promising broad-spectrum activities against all the test isolates. For clinical isolates, the minimal MIC and MBC values were related to B. cereus and L. monocytogenes strains, whereas for the standard strains, both P. aeruginosa and S. aureus showed the lowest MIC and MBC values under the same conditions.

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“…Rech. f. [21,22], Z. hispanica L. [23], Z. pedicellata Pazij & Vved. [24,25], Z. persica Bunge [4,13,25,26], Z. taurica subsp.…”

mentioning

confidence: 99%

“…bungeana [20], Z. clinopodioides subsp. rigida [21,22], Z. hispanica [23], Z. pamiroalaica [36], Z. pedicellata [24,25], Z. persica [4,13,25,26], Z. taurica subsp. cleonioides [27], Z. tenuior [13,[28][29][30][31][32][33][34] Z. vichodceviana [25].…”

mentioning

confidence: 99%