Intravenous diazepam for psychiatric reactions following open-heart surgery

McClish, A; Andrew, Deborah; Tétreault, L

doi:10.1007/bf03005870

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1969

1996

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Cited by 12 publications

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“…When given orally, intramuscularly or intravenously it produces sedation and calmness and has muscle relaxant properties. It can produce unconsciousness when given in large doses intravenously and as such it has been used as an induction agent (Brown & Dundee 1968; McClish 1966) for general anaesthesia. It has become widely used to produce sedation in the nervous dental patient.…”

Section: Introductionmentioning

confidence: 99%

Sedation for Conservative Dentistry

Keilty¹,

Blackwood²

1969

Int J Clinical Practice

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Section: Introductionmentioning

confidence: 99%

Sedation for Conservative Dentistry

Keilty¹,

Blackwood²

1969

Int J Clinical Practice

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Postoperative Delirium

Ashton²,

1995

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We conducted an on-line search and manual searches for 1966 through 1992 to determine the incidence, diagnosis, risk factors, and treatment of postoperative delirium. Of the 374 citations found, 277 articles were excluded after criteria of relevance were applied. After methodologic criteria for validity were applied to the remaining 80 articles, 26 studies were retained for the final information synthesis. The incidence of postoperative delirium was 36.8% (range, 0% to 73.5%). Primary reasons for this disparity were insufficient sample size and inconsistent application of numerous diagnostic tools. One study provided statistically significant data that demonstrated that postoperative delirium is underdiagnosed by physicians and nurses. Four of the articles that met the established criteria provided risk factor data. Although age, preoperative cognitive impairment, and the use of anticholinergic drugs were significantly associated with postoperative delirium, gender, type and route of anesthesia, and sleep deprivation were not. Two studies demonstrated a decreased incidence of postoperative delirium when patients underwent preoperative psychiatric counseling or participated in a structured perioperative program. These findings indicate a need for (1) accurate incidence data with further definition of risk factors and (2) studies that address the diagnosis and treatment of this common postoperative problem.

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