Intravesical electrical stimulation in the treatment of micturition dysfunction in children

Gladh, Gunilla; Mattsson, Sven; Lindström, Sivert

doi:10.1002/nau.10078

Cited by 42 publications

(49 citation statements)

References 26 publications

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“…Other reports of end-organ stimulation exist [12]. A recent study has cited the benefit of stimulation of the bladder wall with electrodes on the end of a urethral catheter in the bladder in children [13]. Urinary retention in these individuals was due to a variety of disorders, and periodic stimulation resulted in improved micturition.…”

Section: Introductionmentioning

confidence: 99%

Bladder-wall and pelvic-plexus stimulation with model microstimulators: Preliminary observations

Walter

FitzGerald²,

Wheeler³

et al. 2005

JRRD

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Abstract-Severe urinary retention is not a common condition, but may occur following some pelvic surgeries or other medical conditions. Electrical stimulation of the bladder has been examined as a means of managing this difficult problem. We conducted preliminary investigations in cats to prove the hypothesis that pelvic-plexus (bladder-neck) stimulation would produce greater micturition response with reduced side effects, such as animal movement or discomfort, than bladder-wall stimulation with electrodes implanted higher on the bladder wall. We used model microstimulators that mimic the look and function of commercial microstimulators, but that we constructed. We instrumented four female cats during a survival surgery. Animals recovered well and studies were conducted over a 1-month period in the conscious animal and under anesthesia. We performed a variety of studies with different stimulation parameters and electrode locations to evaluate our hypothesis. In the active animal, we supplied only low currents, but two animals responded to stimulation with bladder contractions and voiding. Following anesthesia, higher stimulating currents resulted in greater bladder contractions during stimulation in two of the three animals. In two cases, pelvic-plexus (bladder-neck) stimulation induced greater micturition responses than direct bladderwall stimulation. In conclusion, we learned from these preliminary observations that stimulation at the pelvic plexus (bladder neck) may induce a better micturition response than stimulation higher on the bladder-wall. Newly available commercial microstimulators should be further studied for the treatment of urinary retention.

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Section: Introductionmentioning

confidence: 99%

Bladder-wall and pelvic-plexus stimulation with model microstimulators: Preliminary observations

Walter

FitzGerald²,

Wheeler³

et al. 2005

JRRD

View full text Add to dashboard Cite

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“…[1][2][3][4][5] In an earlier study we showed that a sawtooth waveform was equally effective as a square wave for inducing a detrusor contraction if the average input charge was the same. The study also revealed that the average power could be reduced without decreasing the efficacy of the stimulation by changing the frequency or pulse duration.…”

Section: Discussionmentioning

confidence: 97%

“…[1][2][3][4][5] However, the technique has not found wide clinical acceptance because the treatment success rate is not consistent and the results are difficult to reproduce. 1,6 This might be due to patient selectio n, but very likely the influence of methodological issues such as type of stimulation parameters will be important too.…”

Section: Introductionmentioning

confidence: 98%

Evaluating the use of different waveforms for intravesical electrical stimulation: A study in the rat

Bock

Dirckx

Wyndaele

2010

Neurourology and Urodynamics

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Charge-balanced waveforms, which are more preferred by patients, are equally effective in evoking IVES-induced detrusor contraction as monophasic square pulse waveforms. Thus, it can be beneficial in clinical practice to replace the monophasic square pulse waveform for IVES by charge-balanced waveforms. Furthermore, the stimulation power and thus the requested energy can be reduced by changing the waveform. This can be important for electrical stimulation using implanted batteries.

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“…There is evidence that electrotherapy in adults has the potential to improve detrusor contractility and facilitate complete bladder emptying [Thon et al, 1991;Jonas et al, 2001;Primus et al, 2001]. Gladh et al [2002] investigated the e¡ect of intravesical electrical stimulation on the emptying ability of children with both neurogenic and idiopathic detrusor underactivity and noted that voiding was normalized following treatment in 85% of children.The e¡ect was long lasting in 72%; gains being more marked in children with idiopathic rather than neurogenic detrusor dysfunction. Other studies suggest that electrical therapy in children with neurogenic bladder dysfunction is associated with improved bladder storage and enhanced emptying, but may only generate a minimal improvement in continence.…”

Section: Paediatric Applicationmentioning

confidence: 99%

A review of non‐invasive electro neuromodulation as an intervention for non‐neurogenic bladder dysfunction in children

Bower

Yeung

2003

Neurourology and Urodynamics

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There are clear benefits from the use of electroneuromodulation in children with differing forms of voiding dysfunction. The treatment approach is independent of cognitive and pharmacological therapy, is minimally invasive, and free of side effects. To date, there are no clinical variables that reliably predict efficacy of electrotherapy in the various presentations of over and under active detrusor, sphincter dyssynergia, or irritative symptoms.

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Intravesical electrical stimulation in the treatment of micturition dysfunction in children

Abstract: It is concluded that IVES is a promising method to treat the underactive detrusor in children.

Cited by 42 publications

References 26 publications

Bladder-wall and pelvic-plexus stimulation with model microstimulators: Preliminary observations

Bladder-wall and pelvic-plexus stimulation with model microstimulators: Preliminary observations

Evaluating the use of different waveforms for intravesical electrical stimulation: A study in the rat

A review of non‐invasive electro neuromodulation as an intervention for non‐neurogenic bladder dysfunction in children

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