Intravitreal bevacizumab for choroidal neovascularization associated with Best's disease

Pediatric genetic macular and choroidal diseases

“…While there is no prophylaxis or treatment, per se, for Best disease, these patients should be monitored by an ophthalmologist. Yearly examinations are critical for helping to prevent the development of amblyopia, for identifying and treating commonly co-occurring conditions such as hyperopia and angle closure glaucoma, and for identifying CNVM formation and treating it, most commonly with intravitreal anti-VEGF (vascular endothelial growth factor) injections [54][55][56][57][58][59][60]. Furthermore, patients should be educated on the warning signs of CNVM, decreased vision or increased metamorphopsia, which should provoke a more urgent examination.…”