Intravitreal triamcinolone acetonide for treatment of acute nonarteritic anterior ischemic optic neuropathy

Abstract

The clinical courses of all three patients presented suggest that an intravitreal high-dosage injection of triamcinolone acetonide may not be markedly effective in increasing visual acuity after acute NAION.

Non-arteritic anterior ischemic optic neuropathy: role of systemic corticosteroid therapy

“…Use of intravitreal triamcinolone acetonide for treatment of NA-AION There have recently been two contradictory studies on this topic [34,35]. Jonas et al [34], in three patients, found that it had no beneficial effect on visual acuity.…”

Intravitreal bevacizumab for the treatment of nonarteritic anterior ischemic optic neuropathy: a prospective trial

“…Studies involving intravitreal steroid injection [10][11][12][13] have demonstrated improvement in visual acuity over 80% of reported cases.…”

“…[10][11][12] In addition, although avoiding systemic toxicity, intravitreal steroids carry a significant risk of ocular complications such as glaucoma and cataract. 14 Bevacizumab is a local therapy that has potent antiinflammatory properties, and has been used extensively to treat edema of the retina in a safe and efficacious manner.…”

Management of non-arteritic anterior ischemic optic neuropathy

“…Jonas et al [35], in three patients, found that it had no beneficial effect on visual acuity. Kaderli et al [36], in four eyes, reported visual acuity improvement, but without any improvement in visual fields; however, that study had some notable flaws [37].…”