Within the next thirty years the evolutionary approach to aero engine development will struggle to keep abreast with increasingly stringent environmental targets. Therefore radical approaches to aeroengine development in terms of energy savings need to be considered. One particular concept involves the inclusion of a pressure-rise combustion system, within the architecture of an aero-engine, to provide additional shaft power. The nutating disc engine concept is a strong contender due to its power density. The feasibility of the nutating disc engine has been previously investigated for unmanned vehicle applications. However, this paper investigates the performance benefits of incorporating a nutating disc core in a larger geared open rotor engine for a potential entry in to service in 2050. In addition, a methodology is presented to estimate the size and weight of the nutating disc core. This methodology is pivotal in determining the overall performance of the novel aero-engine cycle. The outcome of this study predicts a potential 9.4% fuel burn benefit, over a state of the art geared open rotor in the year 2050. In addition, the sensitivity of the nutating disc design variables was explored. This showcases a pessimistic design and an optimistic design, showing the range of possible fuel burn benefits compared to a comparable year-2000 aircraft mission. Highlights • The nutating disc engine, is a power-dense internal combustion engine that claims high thermal efficiency. • This study investigates the benefit derived from integrating a Dual-cycle (Otto and Diesel) within a Brayton cycle. • A methodology to predict the size and weight of the nutating disc engine is presented. This is essential to determine aircraft mission level fuel burn benefits/penalties • When the nutating disc engine is integrated into the architecture of a year 2050 geared open rotor and aircraft, the potential fuel-burn benefit is 9.4% relative to a year 2050 baseline aircraft.