Introduction to Photobiology

Baron, Elma D.; Suggs, Amanda

doi:10.1016/j.det.2014.03.002

Cited by 49 publications

(33 citation statements)

References 24 publications

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“…Sunlight consists mostly of short wavelength ionizing radiation (cosmic, gamma, and X-rays) and long wavelength non-ionizing radiation (UV, visible, and infrared) [48]. UVR is the area of the electromagnetic spectrum that is considered biologically the most active and therefore of greatest impact on health and disease [49]. For convenience, we separate UV somewhat arbitrarily into UVA (315-400 nm), UVB (280-315 nm) and UVC (100-280 nm).…”

Section: The Sun As Origin Of the Electromagnetic Energymentioning

confidence: 99%

Sunlight and Herpes Virus

Mazzarello¹,

Ferrari²,

Decandia³

et al. 2020

Human Herpesvirus Infection - Biological Features, Transmission, Symptoms, Diagnosis and Treatment

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The Herpesviridae are a family of viruses widely spread in nature that can infect a wide variety of species. After the primary infection, the human alphaherpesvirinae sub-family remains quiescent in the nerve ganglia from which it can periodically reactivate, causing clinical manifestations. Although spontaneous recurrences are possible, a wide variety of internal and external triggers may lead to transformation of the Herpes Simplex and Varicella-Zoster Viruses from a dormant to a proliferative state. Sunlight is a potent stimulus for the alphaherpesvirinae reactivation. The purpose of this paper is to analyze various features of this correlation and several steps you can take to lower your risk of triggering a herpes outbreak after sun exposure. Learning how to reduce the recurrence is extremely important and it is necessary: to perform a gradual and progressive sun exposure; to know what garments to wear; to know the environmental conditions of exposure; to know each skin phototype; to use a protective product against UVB and UVA with sun protection factor suitable for each phototype and environmental conditions.

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Section: The Sun As Origin Of the Electromagnetic Energymentioning

confidence: 99%

Sunlight and Herpes Virus

Mazzarello¹,

Ferrari²,

Decandia³

et al. 2020

Human Herpesvirus Infection - Biological Features, Transmission, Symptoms, Diagnosis and Treatment

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“…Approximately 5% of UVB is present in terrestrial sunlight. UVC is typically filtered by the ozone layer (Baron and Suggs, ).…”

Section: The Electromagnetic Spectrummentioning

confidence: 99%

“…The depth of light penetration is critical for phototherapy. UVB is generally absorbed in the epidermis and upper dermis, whereas UVA (because of its longer wavelengths) penetrates well into the dermis (Baron and Suggs, ). UVB radiation primarily acts on cells at the epidermis and the epidermodermal junction, whereas UVA radiation affects epidermal and dermal components, especially dermal blood vessels (Weichenthal and Schwarz, ).…”

Section: How Phototherapy Workmentioning

confidence: 99%

Ultraviolet phototherapy for cutaneous diseases: a concise review

Vangipuram

Feldman

2015

Oral Diseases

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Phototherapy is the use of non‐ionizing radiation, primarily in the ultraviolet spectrum, to treat disease. In dermatology, ultraviolet (UV) phototherapy remains an established, lower cost, and often preferred option for many common skin conditions, despite the introduction of newer potent biologics. This article introduces a principal therapeutic modality in the treatment of psoriasis, atopic dermatitis (eczema), vitiligo, and morphea among other diseases where oral manifestations may be present, providing basic information about the use of UVA, UVB, and PUVA. Practical considerations and side effects of phototherapy are described. Phototherapy is an effective treatment for many illnesses and carries a relatively benign side‐effect profile.

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“…Photoaging is strongly correlated with sun exposure, with both UVA (320–400 nm) and UVB (290–320 nm) radiation contributing to its progression [36]. Most UVB is absorbed in the epidermis, where it causes sunburn and damages cellular DNA through the formation of cyclobutane pyrimidine dimers and pyrimidine (6–4) pyrimidone photoproducts [37, 38]. DNA damage that is not adequately repaired can lead to increased cellular senescence, apoptosis, and carcinogenesis [37].…”

Section: Introductionmentioning

confidence: 99%

“…DNA damage that is not adequately repaired can lead to increased cellular senescence, apoptosis, and carcinogenesis [37]. UVA penetrates deeper into the dermal layer, damaging DNA, proteins, and lipids indirectly through the generation of reactive oxygen species (ROS), as well as breaking down collagen through the activation of the tissue remodeling matrix metalloproteinases (MMPs) [38]. Sirtuins play a role in both UVA and UVB-mediated events, suggesting that they could be key participants in photoaging.…”

Section: Introductionmentioning

confidence: 99%

Sirtuins in Skin and Skin Cancers

Garcia-Peterson

Wilking-Busch²,

Ndiaye³

et al. 2017

Skin Pharmacol Physiol

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The sirtuins are a family of proteins that comprise class III of the histone deacetylases. These NAD+-dependent proteins have been found to be intricately involved in a variety of important and skin-relevant cellular functions and processes, including aging, UV damage response, oxidative stress, and wound repair. In addition, recent research is unraveling the role of sirtuins in a variety of skin diseases, including melanoma and nonmelanoma skin cancers. In this review, we provide a discussion on the potential roles and implications of different sirtuins in skin-specific cellular processes, which may have relevance to skin health and skin diseases. Based on the available literature, the sirtuins appear to be important targets in the management of a variety of skin diseases from cosmetic (e.g., skin aging) to fatal conditions (e.g., melanoma).

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Introduction to Photobiology

Cited by 49 publications

References 24 publications

Sunlight and Herpes Virus

Sunlight and Herpes Virus

Ultraviolet phototherapy for cutaneous diseases: a concise review

Sirtuins in Skin and Skin Cancers

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