Invasive Squamous Cell Carcinoma of the Conjunctiva

Iliff, W. Jackson; Marback, Roberto Lorens; Green, W R

doi:10.1001/archopht.1975.01010020125005

Cited by 132 publications

(28 citation statements)

References 2 publications

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“…17 30 We noted a slightly higher incidence (13%), probably reflecting a tertiary referral practice. Deep corneal stromal invasion and involvement of anterior chamber structures suggest intraocular invasion 17…”

Section: Discussionmentioning

confidence: 60%

See 1 more Smart Citation

Intraepithelial and invasive squamous cell carcinoma of the conjunctiva: analysis of 60 cases

Tunç

Char

Crawford

et al. 1999

British Journal of Ophthalmology

203

149

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Section: Discussionmentioning

confidence: 60%

“…17 30 36 38Erie and associates30 reported 13% of patients had a history of malignant skin tumours. Twelve (20%) of our patients had skin malignancies; 11 were basal cell and one was an epidermoid carcinoma.…”

Section: Discussionmentioning

confidence: 99%

Intraepithelial and invasive squamous cell carcinoma of the conjunctiva: analysis of 60 cases

Tunç

Char

Crawford

et al. 1999

British Journal of Ophthalmology

203

149

View full text Add to dashboard Cite

show abstract

“…Deep corneal stromal invasion and involvement of the anterior chamber structures suggest intraocular invasion [28]. Iliff et al [10] reported intraocular invasion in 2 of 27 patients with conjunctival SCC. Erie et al [11] described 22 patients with SCC of whom 2 had intraocular invasion.…”

Section: Discussionmentioning

confidence: 99%

“…Although the reported incidence rate ranges from 0.1 to 1.9 per 100,000 persons [4,5,6], OSSN remains the most common ocular surface tumor and conjunctival SCC is the most common ocular malignancy [7,8]. Conjunctival SCC has the potential to locally invade as well as metastasize, with a few case series [9,10,11,12] and case reports [13,14,15,16] identifying intracorneal, intraocular and orbital invasion [17] by conjunctival SCC.…”

Section: Introductionmentioning

confidence: 99%

Conjunctival Squamous Cell Carcinoma with Corneal Stromal Invasion in Presumed Pterygia: A Case Series

Mendoza¹,

Craven

et al. 2018

Ocul Oncol Pathol

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Aim: To describe 4 cases of conjunctival squamous cell carcinoma (SCC) with corneal stromal invasion. Methods: Retrospective, clinicopathologic case series. Results: All patients had prior resections of presumed pterygia. The degree of corneal involvement dictated the extent of surgical management. One eye with localized invasion was treated with lamellar keratoplasty and plaque brachytherapy. Another case with widespread invasion warranted penetrating keratoplasty and eventual enucleation. Two cases were treated medically prior to surgical intervention: one with localized invasion was treated with topical interferon and retinoic acid; another with significant inflammation was treated with doxycycline and fluorometholone. The patient who underwent keratoplasty and brachytherapy had no recurrence after 7 years of follow-up. Those initially treated medically had resections of recurrence but ultimately required enucleation. Histologically, specimens demonstrated SCC invading the deep corneal stroma, with 2 tumors of the mucoepidermoid type. Conclusions: This series demonstrates the importance of maintaining clinical suspicion of conjunctival squamous neoplasia in pterygia. We recommend that all excised pterygia be submitted for histopathologic evaluation and be carefully evaluated for dysplasia and variants of SCC associated with increased risk of intraocular invasion. Undetected ocular surface squamous neoplasia may give rise to potentially vision- and eye-threatening invasive corneal SCC.

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“…Le carcinome épidermoïde a été la deuxième tumeur de notre série, sur 19 cas répertoriés 16 sont des cancers conjonctivaux avec une prédominance de la localisation limbique respectée [10,11].…”

Section: Discussionunclassified

Aspects épidémiologiques et cliniques des cancers oculaires primitifs du mélanoderme : notre expérience à propos de 111 cas

Seck¹,

Agboton²,

Guèye³

et al. 2015

Journal Français d'Ophtalmologie

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Invasive Squamous Cell Carcinoma of the Conjunctiva

Cited by 132 publications

References 2 publications

Intraepithelial and invasive squamous cell carcinoma of the conjunctiva: analysis of 60 cases

Intraepithelial and invasive squamous cell carcinoma of the conjunctiva: analysis of 60 cases

Conjunctival Squamous Cell Carcinoma with Corneal Stromal Invasion in Presumed Pterygia: A Case Series

Aspects épidémiologiques et cliniques des cancers oculaires primitifs du mélanoderme : notre expérience à propos de 111 cas

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