With an innovative perspective on the social character of ignorance production, agnotology has been a fruitful approach for understanding the social and epistemological consequences of the interaction between industry and scientifi c research. In this paper, I argue that agnotology, or the study of ignorance, contributes to a better understanding of commercially driven research and its societal impact, showing the ways in which industrial interests have reshaped the epistemic aims of traditional scientifi c practices, turning them into mechanisms of ignorance production. To do so, I examine some of the main contributions to agnotology and provide a taxonomy of practices of ignorance construction common in commercially driven research today. In particular, I present the tobacco industry's campaign against the health hazards of smoking as a paradigmatic case of ignorance production, identifying fi ve central strategies. I then argue that the same strategies have been used in three other cases -global warming, pharmaceuticals, and the 2008 fi nancial crisis.