Inverted schneiderian papilloma of the supraglottis: Case report

Abstract

Inverted schneiderian papillomas are rare benign tumors, most often arising from the sinonasal mucosa. We describe a case of a 59-year-old female with an inverted papilloma of the supraglottis. This is the first reported case of a supraglottic-presenting inverted papilloma. Although rare, this case demonstrates that these tumors should be considered during workup of supraglottic laryngeal masses. Laryngoscope, 127:2830-2832, 2017.

Inverted Papilloma of the Epiglottis: A Rare Case

“…6 The reported patient with supraglottic IP had a history of regular smoking and intermittent gastroesophageal reflux events; the chronic inflammation that is a likely consequence of gastric reflux and smoking is a plausible explanation for laryngeal IP. 8 In the case of subglottic IP, no suspected cause was found in a 4-year-old boy. 9 The patient of our case was a healthy adult with no past history except for hypertension and diabetes; it is not possible to identify the cause of supraglottic IP and which hypothesis played a crucial role in our case.…”

“…1 To date, ectopic occurrence of IP arising from the outside the sinonasal tract has been reported in the nasopharynx, oropharynx, middle ear, mastoid, temporal bone, supraglottis, subglottis, and lacrimal sac. 2,[5][6][7][8][9][10] However, IP involving the larynx as a primary lesion is extremely rare. To the best of our knowledge, there are only 2 cases of IP arising from the larynx reported in the English literature.…”

“…To the best of our knowledge, there are only 2 cases of IP arising from the larynx reported in the English literature. 8,9 The exact etiology of IP is not known. Although the etiology of sinonasal IP remains controversial, human papilloma virus, smoking, industrial exposures, cell cycle-related proteins, angiogenic factors, and chronic inflammation have been suggested.…”