Investigação Fitoquímica e Avaliação da Atividade Hemolítica e Toxicológica do extrato etanólico obtido da mistura de sementes e vagens de Caesalpinia echinata Lam / Phytochemical Investigation and Evaluation of Hemolytic and Toxicological Activity of the ethanol extract obtained from the mixture of seeds and pods of Caesalpinia echinata Lam

Abstract

Caesalpinia echinata (Fabaceae) known as Pau Brasil is one of the species found in the Atlantic Forest and is used in folk medicine as an astringent, healing, odontoalgic and tonic. The present study aimed to perform the phytochemical screening through thin layer chromatography, in search of new sources of bioactive secondary metabolites and to investigate the ethanolic extract of the mixture of seeds and pods of the C. de echinata (EESVCe) for hemolytic activity (front the erythrocyte membrane) and toxicological (front the Artemia salina). The plant material was collected at the Federal University of Pernambuco and the molecules identified in the screening were: coumarins, flavonoids, saponins, tannins and terpenes. The evaluation of the hemolytic activity of the EESVCe