Investigating anthocyanin contents and in vitro tumor suppression properties of blueberry extracts prepared by various processes

Kazan, Aslihan; Sevimli-Gur, Canan; Yeşil-Çeliktaş, Özlem; Dunford, Nurhan Tugut

doi:10.1007/s00217-015-2577-9

Cited by 15 publications

(2 citation statements)

References 23 publications

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“…Their phenolic compounds, namely anthocyanins, protect nerve cells (PC 12) from cell-damaging oxidative stress in a dose-dependent manner. In recent years, several studies have reported that anthocyanins exhibit a wide range of biological properties, including antioxidant, antimicrobial, anti-inflammatory (COX1 and COX2), as well as anticarcinogenic and neuroprotective effects (Kazan et al, 2016;Svar-Gajic et al, 2017).…”

Section: Introductionmentioning

confidence: 99%

Changes in colour parameters and anthocyanin content of aseptically filled sour cherry juice during storage

et al. 2022

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To overcome the problems of seasonality and geographical location in fruit production and processing, the production of aseptic semi-finished juice is an excellent solution. Even without refrigeration, aseptic pressing has a shelf life of more than a year, making it possible to produce finished products all year round. The production technology involves the addition of ascorbic acid to the pulp to fix or preserve colour. There is an increasing customer demand for ascorbic acid substitutes on the international market. In Hungary, one of the most important exports is aseptic sour cherry juice. In our work, ascorbic acid used for colour fixation was replaced by acerola concentrate. The anthocyanin content and colour coordinate values (L*, a*, b*, H, C) of aseptically filled sour cherry juice were determined and compared with the control sample during the 12 months of storage.

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Section: Introductionmentioning

confidence: 99%

Changes in colour parameters and anthocyanin content of aseptically filled sour cherry juice during storage

et al. 2022

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“…On the other hand, some flavonoid contained in dry fruits of this genera have both antimutagenic and antitumoral activity. Preservation and normalization effects have been observed in the cellular cycle (Vattem;Ghaedian;Shetty 2005;Gambini et al, 2015); DNA molecule repair in cellular lines of colon cancer, induction of apoptosis, inhibition of tumor invasion and angiogenesis, as well as decrease in swelling processes (Kumar;Dhatwalia;Dhawan, 2016;Kazan et al, 2016;Kazan et al, 2017). Inhibition of atherogenesis, quercetin-mediated plaque aggregation, increase in neuronal signalization and increase in insulin secretion, have also been found (Martineau et al, 2006;Perez;Duarte 2010;Krikorian et al, 2010).…”

Section: Introductionmentioning

confidence: 99%

Microwave-assisted extraction in dry fruit of andean species Vaccinium meridionale: Experimental conditions on the recovery of total polyphenols

2017

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Due to their nutraceutical properties, the fruits of the species Vaccinium meridionale, which inhabit the Andean region, are of scientific interest. Microwave-assisted extraction has been applied to different vegetal matrices for to extract efficiently polyphenolic compounds. In this work we study in microwave assisted extraction processes, the effect on the extraction of total polyphenols in dried fruits of Vaccinium meridionale, using response surface methodology. The main objective of this research was to analyze the relationships between power, temperature, solid-liquid ratio, time and ethanol concentration in aqueous media on the effectiveness of total polyphenols recovery in dry fruits of Vaccinium meridionale. A central composite design face-centered with three levels for each variable was used: P = 300 -900 W; T = 70 -110 °C; L:S rat. = 30:1 -70:1 w/w; t = 5 -15 min; [EtOH] = 0 -80%. In this sense, the effect of the input variables on the recovery of total polyphenols, the optimization process for maximum extraction, and the comparison to other solid-liquid extractions in terms of quantity of total polyphenols, are reported. It was found that the significant variables in the extraction process were ethanol concentration, temperature and time; the best yields were obtained in the range [EtOH] = 44 -49%, T = 110 °C, and t = 10 -15 min. In terms of quantity, time and consumption of energy, microwave-assisted extraction technique is more efficient than other solid-liquid extraction processes for the extraction of total polyphenols.Index terms: Folin-Ciocalteu method; response surface methodology (RSM); nutraceutical properties. RESUMODevido a suas propriedades nutracêuticas em termos do conteúdo de polifenóis totais, os frutos da espécie andina Vaccinium meridionale tem associado um grande interesse cientifico. A extração assistida por microondas tem sido utilizada em diferentes matrizes vegetais para a remoção de forma eficiente de compostos polifenólicos que apresentam uma atividade biológica. Neste artigo são apresentados os principais resultados experimentais obtidos em diferentes processos de extração assistida por microondas, com respeito à quantia de polifenóis totais removidos em frutos secos de Vaccinium meridionale por meio da metodologia da superfície de resposta. O principal objetivo desta pesquisa foi analisar as relações entre as variáveis independentes da potência, a temperatura, a relação sólido-líquido, tempo e concentração de etanol com respeito à quantidade polifenóis totais extraídos de frutos secos de Vaccinium meridionale. Foi utilizado um desenho composto centrado nas caras com três diferentes níveis para cada variável: P = 300 -900 W; T = 70 -110 °C; L:S rat. = 30:1 -70:1 w/w; t = 5 -15 min; [EtOH] = 0 -80%. Foi utilizado o método de Folin-Ciocalteu para a quantificação de polifenóis totais com ácido gálico como molécula de referência. Neste sentido, foi reportado neste trabalho o efeito dos fatores de entrada com respeito a quantidade de polifenóis totais removidos, o process...

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Xu¹,

Li²,

Wang³

2019

Bioactive Factors and Processing Technology for Cereal Foods

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Investigating anthocyanin contents and in vitro tumor suppression properties of blueberry extracts prepared by various processes

Cited by 15 publications

References 23 publications

Changes in colour parameters and anthocyanin content of aseptically filled sour cherry juice during storage

Changes in colour parameters and anthocyanin content of aseptically filled sour cherry juice during storage

Microwave-assisted extraction in dry fruit of andean species Vaccinium meridionale: Experimental conditions on the recovery of total polyphenols

Corn

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