Investigating recurrent angio-oedema

Fitzharris, Penny; Jordan, Anthony

doi:10.1136/bmj.d6607

Cited by 5 publications

(4 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…If the use of an ACE inhibitor is continued after an incident, the rate of recurrent angioedema increases to 187 per 1,000 person–years, with, on average, 11 months to recurrence, according to a study covering 51,752 person–years of ACE inhibitor use 28 . After drug withdrawal, the tendency to develop angioedema usually abates but may persist for months or even years 29 , 30 . It is difficult to rationalize how such episodes can occur after stopping the ACE inhibitor, and indeed this is not in accordance with the usual criteria for causality assessment for acutely occurring ADRs.…”

Section: Description Of the Phenotypementioning

confidence: 99%

Phenotype Standardization of Angioedema in the Head and Neck Region Caused by Agents Acting on the Angiotensin System

Wadelius

Marshall

Islander

et al. 2014

Clin Pharmacol Ther

View full text Add to dashboard Cite

Angioedema is a potentially life-threatening adverse reaction to angiotensin-converting enzyme inhibitors and angiotensin receptor blockers. To study the genetic etiology of this rare adverse event, international consortia and multicenter recruitment of patients are needed. To reduce patient heterogeneity, we have standardized the phenotype. In brief, it comprises swelling in the head and neck region that first occurs during treatment. It should not coincide with urticaria or have another likely cause such as hereditary angioedema.

show abstract

Section: Description Of the Phenotypementioning

confidence: 99%

Phenotype Standardization of Angioedema in the Head and Neck Region Caused by Agents Acting on the Angiotensin System

Wadelius

Marshall

Islander

et al. 2014

Clin Pharmacol Ther

View full text Add to dashboard Cite

show abstract

“…Non-histaminergt angioødem kan udløses af bradykinin (bradykinergt angioødem) og komplement-deriverede mediatorer (5,22,23 (24). Aktiviteten af bradykinin kataboliserende enzymer kan have betydning for patienters individuelle risiko for angioødem.…”

Section: Non-histaminergt Angioødemunclassified

“…Autoimmun thyreoideasygdom kan ses med angioødem (3)(4)(5)22). Der har vaeret fokus på andre autoimmune årsager til udvikling af angioødem, men mekanismer og sammenhaenge mangler fortsat afklaring.…”

Section: Non-histaminergt Angioødemunclassified

Angioødem – udredning og behandling

Rasmussen¹,

Bindslev‐Jensen²,

Bygum³

2012

Tidsskriftet

View full text Add to dashboard Cite

show abstract

“…Urticaria is defined as the vascular reaction of the upper dermis marked by itching and the transient appearance of raised patches that are redder or paler than the surrounding skin. 1 Angiotensin-converting enzyme inhibitors (ACEIs), non-steroid anti-inflammatory drugs (NSAID), neuromuscular blockers and penicillin are the most common medications held responsible for angioedema, 2 but it can also be observed as a rare but potentially life-threatening adverse effect of selective serotonin reuptake inhibitors (SSRIs). There are 4 reported cases of angioedema associated with SSRIs in the literature.…”

Section: Introductionmentioning

confidence: 99%