Investigating the phenomenon of “cognitive-motor interference” in multiple sclerosis by means of dual-task posturography

Prosperini, Luca; Castelli, Letizia; Sellitto, Giovanni; Luca, Francesca De; Giglio, Laura De; Gurreri, Flavia; Pozzilli, Carlo

doi:10.1016/j.gaitpost.2015.02.002

Cited by 37 publications

(57 citation statements)

References 33 publications

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“…Generally, our observations support the notion that cognitive impairments negatively affect posture stability in PwMS (Kalron et al, 2011;Negahban et al, 2011;Negahban et al, 2013;Prosperini et al, 2015). However, we found that the cognitive domain, related to poor postural control in PwMS, was different between disability levels.…”

Section: Discussionsupporting

confidence: 90%

“…This belief is based on several research paradigms exploring the association between these two common symptoms. According to several motorcognitive dual-task trials, cognitive loading negatively affects postural control, resulting in increased sway rate and center of pressure (CoP) movement (Kalron et al, 2011;Negahban et al, 2013;Prosperini et al, 2015). Furthermore, cross-sectional epidemiological studies have confirmed that PwMS with reduced cognitive abilities have an increased risk of falling and suffer from a high rate of mobility deteriorations (Kalron and Achiron, 2013;Kalron, 2014).…”

Section: Introductionmentioning

confidence: 99%

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The relationship between static posturography measures and specific cognitive domains in individuals with multiple sclerosis

Kalron

2016

International Journal of Rehabilitation Research

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There are still limitations as to the understanding of the cognitive-postural control relationship in people with multiple sclerosis (PwMS). The aim of the current study' was to examine the relationship between cognition with measures of posturography in PwMS. The study was cross-sectional comprising 253 PwMS (162 women) with a mean age of 42.0 (SD=14.0). All participants completed a computerized cognitive test battery designed to evaluate multiple cognitive domains (Mindstreams; NeuroTrax) and static posturography tests (Zebris Medical GmbH). PwMS were divided into four levels of disability on the basis of their Expanded Disability Status Scale (EDSS) score: very mild (EDSS: 0-2.0), mild (EDSS: 2.5-3.5), moderate (EDSS: 4.0-5.5), and severe (EDSS: 6.0-6.5; using a walking aid). Significant correlations were observed between cognitive domains and posturography measures. However, the correlations were different between the disability subgroups. For the mild group, significant correlation scores were observed between the balance measures to the executive function and motor skills cognitive domains (Pearson's ρ=∼0.3 and ∼0.4, respectively). As for the moderate group, significant correlation scores were observed in memory and verbal function (Pearson's ρ=∼0.4 and ∼0.4, respectively). Attention was the only cognitive domain correlated significantly with posturography measures in the severe group (Pearson's ρ=∼0.55). Our study found that posturography measures are related to cognition in PwMS. However, the associations vary in terms of cognitive domains and disability levels.

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Section: Discussionsupporting

confidence: 90%

Section: Introductionmentioning

confidence: 99%

The relationship between static posturography measures and specific cognitive domains in individuals with multiple sclerosis

Kalron

2016

International Journal of Rehabilitation Research

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“…Eight studies evaluated the effects of dual-task training on postural stability 34–36,48,61–64. Eight studies evaluated the effects of dual tasks on participants suffering from neurological diseases, such as degenerative cerebellar disorder, Parkinson’s disease, and multiple sclerosis 21,65,66. Twenty-six studies evaluated the effects of dual tasks on postural stability among healthy young and/or elderly participants 16,17,20,67–89.…”

Section: Resultsmentioning

confidence: 99%

“…The average PEDro score for the 42 included studies was computed to be 4.7 out of 10, indicating fair quality of the overall studies. One study scored 7,36 three studies scored 6,21,35,65 20 studies scored 5,16,17,20,34,69–72,74,77,79–84,86,92–95 and 18 studies scored 4 22,48,61–63,66–68,73,75,76,78,81,85,87–89,91…”

Section: Resultsmentioning

confidence: 99%

“…Eight studies evaluating the effects of dual-task performance on postural stability among participants affected by neurological disorders, such as cerebellar disorder, Parkinson’s disease,22,92–94 and multiple sclerosis,21,65,66,91 were included in the review. Significant enhancements in postural stability were reported in one good65 and one fair-quality study 94.…”

Section: Meta-analysis Reportmentioning

confidence: 99%

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Effects of dual tasks and dual-task training on postural stability: a systematic review and meta-analysis

Ghai

Effenberg

2017

CIA

195

132

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The use of dual-task training paradigm to enhance postural stability in patients with balance impairments is an emerging area of interest. The differential effects of dual tasks and dual-task training on postural stability still remain unclear. A systematic review and meta-analysis were conducted to analyze the effects of dual task and training application on static and dynamic postural stability among various population groups. Systematic identification of published literature was performed adhering to Preferred Reporting Items for Systematic Reviews and Meta-analysis (PRISMA) guidelines, from inception until June 2016, on the online databases Scopus, PEDro, MEDLINE, EMBASE, and SportDiscus. Experimental studies analyzing the effects of dual task and dual-task training on postural stability were extracted, critically appraised using PEDro scale, and then summarized according to modified PEDro level of evidence. Of 1,284 records, 42 studies involving 1,480 participants met the review’s inclusion criteria. Of the studies evaluating the effects of dual-task training on postural stability, 87.5% of the studies reported significant enhancements, whereas 30% of the studies evaluating acute effects of dual tasks on posture reported significant enhancements, 50% reported significant decrements, and 20% reported no effects. Meta-analysis of the pooled studies revealed moderate but significant enhancements of dual-task training in elderly participants (95% CI: 1.16–2.10) and in patients suffering from chronic stroke (−0.22 to 0.86). The adverse effects of complexity of dual tasks on postural stability were also revealed among patients with multiple sclerosis (−0.74 to 0.05). The review also discusses the significance of verbalization in a dual-task setting for increasing cognitive–motor interference. Clinical implications are discussed with respect to practical applications in rehabilitation settings.

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Effect of cognitive task complexity on dual task postural stability: a systematic review and meta-analysis

Salihu

Jaberzadeh

2022

Exp Brain Res

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Investigating the phenomenon of “cognitive-motor interference” in multiple sclerosis by means of dual-task posturography

Cited by 37 publications

References 33 publications

The relationship between static posturography measures and specific cognitive domains in individuals with multiple sclerosis

The relationship between static posturography measures and specific cognitive domains in individuals with multiple sclerosis

Effects of dual tasks and dual-task training on postural stability: a systematic review and meta-analysis

Effect of cognitive task complexity on dual task postural stability: a systematic review and meta-analysis

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