Abstract-The purpose of this paper is to investigate the relationship between personality traits and customer-oriented behavior in the Malaysian health tourism hospitals. The respondents wereconsisted of nurses inthe 13 health tourism hospitals in Malaysia. Data were collected by using administered on-site questionnaires and the constructs of this study were developed from past researchers with tested validity and reliability.Multiple regressionswere employed to test the relationship between personality traits and customeroriented behavior.The findings of this study revealed that openness to experience and conscientiousness were significantly and positively related to customer-oriented behavior. These findings may be of help to healthcare managers to select the right candidates for customer-oriented nurses.IndexTerms-Customer-oriented behavior, health tourism hospitals, nurses, personality traits.