Investigating the survival and activity of a bacteriophage in the complex colon environment with the use of a dynamic model of the colon (TIM-2)

Maas, Evy; Penders, John; Venema, Koen

doi:10.1016/j.micpath.2023.106061

Cited by 3 publications

(2 citation statements)

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“…NE usually occurs in broiler chickens between 2-6 weeks after hatch and can be classified into clinical and subclinical forms (75). The clinical form is characterized by gaseous lesions, mucosa necrosis, and damage to the intestinal wall, which can lead to a sudden increase in flock mortality (76). The subclinical form is less clear but can cause significant economic losses in the poultry industry, as chronic intestinal mucosal damage can result in poor digestion and absorption of feed, leading to reduced weight gain and increased feed conversion ratio (75,77).…”

Section: Necrotic Enteritis In Broiler Chickensmentioning

confidence: 99%

“…The use of the fermentation models for this kind of research is under development. Maas et al focused on the link between bacterial composition and the virome and mycobiome, since the intestine harbors all these communities and there might be a relevant interplay between them (75,76). Furthermore, the fermentation models should be developed further, for mimicking diseases or mimicking a state of dysbiosis.…”

Section: Future Perspectivesmentioning

confidence: 99%

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Carbohydrate-boosted control of intestinal health

Oost

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Section: Necrotic Enteritis In Broiler Chickensmentioning

confidence: 99%

Section: Future Perspectivesmentioning

confidence: 99%

Carbohydrate-boosted control of intestinal health

Oost

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A review of bacteriophage and their application in domestic animals in a post-antibiotic era

Guo,

Luo,

Hou

et al. 2024

Science of The Total Environment

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Clostridioides difficile infection: history, epidemiology, risk factors, prevention, clinical manifestations, treatment, and future options

Di Bella,

Sanson,

Monticelli

et al. 2024

Clin Microbiol Rev

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SUMMARY Clostridioides difficile infection (CDI) is one of the major issues in nosocomial infections. This bacterium is constantly evolving and poses complex challenges for clinicians, often encountered in real-life scenarios. In the face of CDI, we are increasingly equipped with new therapeutic strategies, such as monoclonal antibodies and live biotherapeutic products, which need to be thoroughly understood to fully harness their benefits. Moreover, interesting options are currently under study for the future, including bacteriophages, vaccines, and antibiotic inhibitors. Surveillance and prevention strategies continue to play a pivotal role in limiting the spread of the infection. In this review, we aim to provide the reader with a comprehensive overview of epidemiological aspects, predisposing factors, clinical manifestations, diagnostic tools, and current and future prophylactic and therapeutic options for C. difficile infection.

show abstract

Investigating the survival and activity of a bacteriophage in the complex colon environment with the use of a dynamic model of the colon (TIM-2)

Cited by 3 publications

References 23 publications

Carbohydrate-boosted control of intestinal health

Carbohydrate-boosted control of intestinal health

A review of bacteriophage and their application in domestic animals in a post-antibiotic era

Clostridioides difficile infection: history, epidemiology, risk factors, prevention, clinical manifestations, treatment, and future options

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