Investigation of cytotoxicity potential of different extracts of Ziziphus mauritiana (Lam) leaf Allium cepa model

Abstract

Graphical abstract

Antioxidant and the ameliorating effect of Allium cepa (Onion) fortified feed against potassium bromate induced oxidative damage in Wistar rats

“…These compounds, as well as other phytochemicals found in onions, have the potential to protect body cells from free radicals linked to oxidative stress, which is characterized as an imbalance between the oxidant and antioxidant systems that favors the former, resulting in changes in redox signaling and control, as well as molecular damage [ 8 , 9 ]. Some researchers have also explored Allium cepa as a bioindicator of environmental pollution [ 10 , 11 ] and to estimate the genotoxic potential of medicinal plants [ 12 , 13 ]. Sulfur-containing compounds found in onions and garlic are attributed to their unique odour and flavour associated with Allium cepa and garlic, hence, constituting about 1 % and 0.5 % of the dry weight of garlic and onions respectively [ 14 ].…”

Genotoxic Activities of Polysaccharides from Cotyledon and Coat of Fermented and Unfermented Annona squamosa L. Seed

“…The root growth inhibition could have occurred as a result of the inhibition of cell division (indicating toxicity) and it is thus an index for estimating general toxicity. It occurs when roots are exposed to extreme pH, or to substances that prevent nutrient uptake (Owolarafe et al, 2020). The inhibitory effects could also be due to cell extension, that is, cessation of root elongation which is correlated with the disappearance of mitotic figures.…”

Cytotoxic Potential of Hydroalcoholic Extract of Annona squamosa L. Fermented Cotyledon

“…The root growth inhibition could have occurred as a result of the inhibition of cell division and it is thus an index for estimating general toxicity. It occurs when roots are exposed to extreme pH, or to substances that prevent nutrient uptake (Owolarafe et al, 2020). The inhibitory effects could also be due to cell extension, that is, cessation of root elongation which is correlated with the decrease in protein concentration observed.…”