Investigation of in vitro antifungal activity of honey

Abstract

The study was aimed at determining the antifungal activities of some honey samples obtained from different geographical locations in Nigeria against some fungal isolates by the method of agar well diffusion. The honey samples were examined for antifungal activity against Aspergillus niger, Aspergillus flavus, Penicillium chrysogenum, Microsporum gypseum, Candida albicans, and Saccharomyces sp. Minimum inhibitory concentration (MIC) and minimum fungicidal concentration (MFC) of the honeys were also determined. Results obtained reveal that the honey samples showed varying levels of inhibitory activity at various concentrations against the fungi tested with zones of inhibition increasing with increasing honey concentration. M. gypseum was the most sensitive of all the fungal isolates studied, while C. albicans was the least sensitive. The MIC and MFC values for the honeys ranged between 12.5 and 50% (v/v). The samples of honey used in the study showed broad spectrum and promising antifungal activity. Nigerian honey can serve as sources of antifungal substances for possible development of antifungal drugs for the treatment of fungal infections.

In vitro antimicrobial activities of Saudi honeys originating from Ziziphus spina‐christi L. and Acacia gerrardii Benth. trees

“…for some yeasts and fungi, such as Aspergillus, Penicillium, Candida, and common dermatophytes (Anyanwu, 2012;Brady, Molan, & Harfoot, 1996;Carter, Blair, Irish, & Shokohi, 2006). This is in line with previous studies regarding the antifungal action of other honey types (Manuka, Medihoney, Nigerian, etc.)…”

Antimicrobial properties and isotope investigations of South African honey

“…), Algeria (Moussa et al . ) and Nigeria (Anyanwu ). These studies provide an important global perspective as it is evident that the antimicrobial activity of honey varies according to composition which is in turn dependent on geographical location, botanical origin, bee sub‐species, season and post‐harvest treatment (Kaskoniene and Venskutonis ).…”

“…It is evident that this area of research has received a plethora of attention, where investigations have provided strong evidence for the antimicrobial properties of honey. Studies have focused on a wide range of geographical regions including Dubai (Al-Waili 2004), New Zealand (Brady et al 2004), Australia (Lusby et al 2005;Irish et al 2011), Portugal (Henriques et al 2005), Argentina (Basualdo et al 2007), Wales (Cooper et al 2008), Spain (Gallardo-Chacon et al 2008), Iran (Khosravi et al 2008), Ireland (Maeda et al 2008), India (Mandal et al 2010), Pakistan (Gulfraz et al 2010), Chile (Sherlock et al 2010), Cuba (Alvarez-Suarez et al 2010) Malaysia (Khoo et al 2010), Greece (Voidaroua et al 2011), Algeria (Moussa et al 2012) and Nigeria (Anyanwu 2012). These studies provide an important global perspective as it is evident that the antimicrobial activity of honey varies according to composition which is in turn dependent on geographical location, botanical origin, bee sub-species, season and post-harvest treatment (Kaskoniene and Venskutonis 2010).…”

Study of Honey as a Sweet Remedy against Fungal Supremacy

“…Due to such protective characteristics, honey studied extensively as alternate medicine. [17] [14] [18] [19]. Irish and co-worker in 2006, [14] studied the clinical isolates of Candida albicans, Candida glabrata, and Candida dubliniensis were tested against four different honeys.…”