The rapid increasing amount of produced water in the deep-water and ultra-deep-water fields, especially those at their later development stages, increases the risk of the occurrence of hydrates plugging. In order to prevent and remediate the hydrates risks, it is important to understand the hydrate formation, slurry flow, and plugging characteristics and mechanisms under high water cuts conditions. In this paper, experiments with high water cuts ranging from 60–100% were conducted using a high pressure flow loop with observation windows. The whole processes of the hydrate formation, slurry flow and plugging is visually seen and recorded, and has been discussed and explained in detail in this paper. Moreover, it is found that the increasing water cuts shorten the induction time, but increase the volume fraction of hydrates. As the water cuts increase, the flow time of the hydrate slurry decreases, which serves as a critical parameter for the safe operation of the pipeline. In addition, different hypothetical mechanisms have been proposed for the medium and high water cuts conditions. We believe that this research can provide theoretical support for the safe transportation of oil and gas development in the high water cut oilfield.