2023
DOI: 10.1109/trpms.2022.3211780
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Investigation of Novel Preclinical Total Body PET Designed With J-PET Technology: A Simulation Study

Abstract: The growing interest in human-grade total body positron emission tomography (PET) systems has also application in small animal research. Due to the existing limitations in human-based studies involving drug development and novel treatment monitoring, animal-based research became a necessary step for testing and protocol preparation. In this simulation-based study two unconventional, cost-effective small animal total body PET scanners (for mouse and rat studies) have been investigated in order to inspect their … Show more

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Cited by 6 publications
(7 citation statements)
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“…
Fig. 1 Axial length and diameter of small animal scanners with axial lengths longer than 90 mm [ 13 , 21 , 28 31 , 38 , 40 48 ]. Only scanners with published results were selected.
…”
Section: Status Of Current Total-body Small-animal Petmentioning
confidence: 99%
See 3 more Smart Citations
“…
Fig. 1 Axial length and diameter of small animal scanners with axial lengths longer than 90 mm [ 13 , 21 , 28 31 , 38 , 40 48 ]. Only scanners with published results were selected.
…”
Section: Status Of Current Total-body Small-animal Petmentioning
confidence: 99%
“…References of the scanners are shown in Table 3
Fig. 2 Volumetric resolution and sensitivity at the center of small animal scanners with axial lengths longer than 90 mm [ 13 , 21 , 28 31 , 38 , 40 48 ], which corresponds to Fig. 1 .
…”
Section: Status Of Current Total-body Small-animal Petmentioning
confidence: 99%
See 2 more Smart Citations
“…This issue inspired extensive efforts to develop affordable alternative systems by research groups around the world. Possible approaches include sparse configurations to reduce the total number of detectors while maintaining a long AFOV [9], the use of alternative, cheaper scintillation materials such as BGO [8] or plastic scintillators [10], and monolithic detector blocks [11].…”
Section: Introductionmentioning
confidence: 99%