Investigation of the anti-aging properties of allicin from &lt;i&gt;Allium sativum&lt;/i&gt; L bulb extracts by a reverse docking approach

Pangastuti, Ardini; Indriwati, Sri Endah; Amin, Mohamad

doi:10.4314/tjpr.v17i4.10

Cited by 7 publications

(4 citation statements)

References 16 publications

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“…Some compounds are known to have acted as elastase inhibitor, that is, epigallocatechin gallate, catechin, procyanidin, and quercetin. [ 3 6 7 8 ]…”

Section: Introductionmentioning

confidence: 99%

Inhibition of pancreatic elastase in silico and in vitro by Rubus rosifolius leaves extract and its constituents

et al. 2020

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“…Some compounds are known to have acted as elastase inhibitor, that is, epigallocatechin gallate, catechin, procyanidin, and quercetin. [ 3 6 7 8 ]…”

Section: Introductionmentioning

confidence: 99%

Inhibition of pancreatic elastase in silico and in vitro by Rubus rosifolius leaves extract and its constituents

et al. 2020

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“…Pangastuti and coworkers [ 172 ] used molecular docking against leukocyte elastase as a protein target to examine the beneficial components of Allium sativum , specifically allicin ( Figure 2 ). Leukocyte elastase is a protein responsible for elastin degradation, which subsequently inhibits OS and the apoptosis cycle and allows this protein to be involved in aging.…”

Section: Anti-aging Natural Compounds From Vegetablesmentioning

confidence: 99%

Vegetables and Their Bioactive Compounds as Anti-Aging Drugs

et al. 2022

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Aging is a continuous process over time that is mainly related to natural alterations in mechanical–biological processes. This phenomenon is due to several factors, including the time and energy of biological processes. Aging can be attributed to biological factors such as oxidative stress, cell longevity, and stem cell senescence. Currently, aging is associated with several diseases, such as neurodegenerative diseases, cancer, and other diseases related to oxidative stress. In addition, certain natural molecules, including those derived from vegetables, have shown the ability to delay the aging process. Their effects are linked to different mechanisms of action, such as tissue regeneration and the activation of longevity and anti-senescence genes. The present work discusses the impact of vegetables, and bioactive compounds isolated from vegetables, against the physiological and pathological aging process and accompanying human diseases.

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“…Allicin is a substance that exhibits a strong antioxidant effect based on free radicals inhibiting [ 318 , 320 ]. It has antifungal and antimicrobic (the antibacterial activity against several Gram-positive and Gram-negative bacterial strains was noticed) properties [ 319 , 321 , 322 ].…”

Section: Allicinmentioning

confidence: 99%

Natural Biocidal Compounds of Plant Origin as Biodegradable Materials Modifiers

Pawłowska

Stepczyńska

2021

J Polym Environ

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The article presents a literature review of the plant origin natural compounds with biocidal properties. These compounds could be used as modifiers of biodegradable materials. Modification of polymer material is one of the basic steps in its manufacturing process. Biodegradable materials play a key role in the current development of materials engineering. Natural modifiers are non-toxic, environmentally friendly, and renewable. The substances contained in natural modifiers exhibit biocidal properties against bacteria and/or fungi. The article discusses polyphenols, selected phenols, naphthoquinones, triterpenoids, and phytoncides that are natural antibiotics. Due to the increasing demand for biodegradable materials and the protection of the natural environment against the negative effects of toxic substances, it is crucial to replace synthetic modifiers with plant ones. This work mentions industries where materials containing natural modifying additives could find potential applications. Moreover, the probable examples of the final products are presented. Additionally, the article points out the current world’s pandemic state and the use of materials with biocidal properties considering the epidemiological conditions.

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Investigation of the anti-aging properties of allicin from <i>Allium sativum</i> L bulb extracts by a reverse docking approach

Cited by 7 publications

References 16 publications

Inhibition of pancreatic elastase in silico and in vitro by Rubus rosifolius leaves extract and its constituents

Inhibition of pancreatic elastase in silico and in vitro by Rubus rosifolius leaves extract and its constituents

Vegetables and Their Bioactive Compounds as Anti-Aging Drugs

Natural Biocidal Compounds of Plant Origin as Biodegradable Materials Modifiers

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