Understanding the response of buildings to wind loads is critical, as these forces can generate significant pressure and suction, potentially leading to structural failure if overlooked. This research was focused on examining the effects of openings on triangular-shaped buildings when subjected to high wind load conditions. Utilizing CAD modeling and Computational Fluid Dynamics (CFD) simulations, the analysis was executed through the ANSYS simulation package. Subsequent Fluid-Structure Interaction (FSI) studies were conducted to ascertain shear stress and lateral deformation. The studies encompassed building models both with and without openings, with the evaluation of induced pressure and velocity. The resultant drag on buildings incorporating openings was discovered to be 6679N lower than those without openings. Furthermore, an analysis employing M25 concrete indicated a 33.133% reduction in lateral deformation in buildings with openings as compared to those without. For buildings constructed with M30 concrete, a 32.173% decrease in lateral deformation was observed. Despite the informative findings, it should be recognized that the investigation was confined to a particular range of wind load conditions and did not consider extreme scenarios. Dynamic wind effects and long-term structural behavior were not included in the current analysis. Therefore, while this study elucidates the importance of wind load analysis and structural reinforcement for maintaining building stability, further research is warranted. Such future investigations should consider broader simulation models, encompassing diverse building shapes and wind load conditions, and account for additional influential factors.