Investigation of the interaction between magnetic nanoparticles surface-coated with carboxymethyldextran and blood cells using Raman spectroscopy

Santana, J.F.B.; Soler, Maria A. G.; Silva, S. W. da; Guedes, M.H.A.; Lacava, Z.G.M.; Azevedo, Ricardo Bentes; Morais, P.C.

doi:10.1016/j.jmmm.2004.11.127

Cited by 9 publications

(8 citation statements)

References 11 publications

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“…The magnetic fluid concentrations tested in the frame of this experiment were similar to those that were shown to induce graduate effects in the case of other microbiological samples [7,8] -the correspondent iron oxide levels being known to have biological effects on blood cells, for instance [9,10].…”

Section: Discussionsupporting

confidence: 64%

Magnetite nanoparticles for biosensor model based on bacteria fluorescence

Poita¹,

Creangă²,

Airinei³

et al. 2009

J. Eur. Opt. Soc.-Rapid Publ.

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Fluorescence emission of pyoverdine -the siderophore synthesized by iron scavenger bacteria -was studied using in vitro cultures of Pseudomonas aeruginosa with the aim to design a biosensor system for liquid sample iron loading. Diluted suspensions of colloidal magnetite nanoparticles were supplied in the culture medium (10 microl/l and 100 microl/l) to simulate magnetic loading with iron oxides of either environmental waters or human body fluids. The electromagnetic exposure to radiofrequency waves of bacterial samples grown in the presence of magnetic nanoparticles was also carried out. Cell density diminution but fluorescence stimulation following 10 microl/l ferrofluid addition and simultaneous exposure to radiofrequency waves was evidenced. The inhibitory influence of 100 microl/l ferrofluid combined with RF exposure was evidenced by fluorescence data. Mathematical model was proposed to approach quantitatively the dynamics of cell density and fluorescence emission in relation with the consumption of magnetite nanoparticle supplied medium. The biosensor scheme was shaped based on the response to iron loading of bacterial sample fluorescence.

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Section: Discussionsupporting

confidence: 64%

Magnetite nanoparticles for biosensor model based on bacteria fluorescence

Poita¹,

Creangă²,

Airinei³

et al. 2009

J. Eur. Opt. Soc.-Rapid Publ.

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“…These RR shifts provide some information about the oxygenation state, as well as the oxidation and spin states, of heme irons (Spiro and Strekas, 1974;Shelnutt et al, 1979;Wood et al, 2001). It was also reported that the oxy-and deoxy-Hb-specific RR shifts in aqueous solutions were applicable for measurement of oxygen saturation (SO 2 ) in erythrocytes interacted with magnetic nanoparticles in vitro (Santana et al, 2005;Soler et al, 2007) and in blood vessels running throughout the abdominal peritoneum of living mice by intravital Raman microscopic analyses (Torres Filho et al, 2005). Some other researchers reported Raman microscopic data on RR shifts at LoT of photodissociated carbon monooxy (CO)-Hb and deoxy-Hb (Ondrias et al, 1981(Ondrias et al, , 1983a.…”

Section: Introductionmentioning

confidence: 96%

Application of “in vivo cryotechnique” to detect erythrocyte oxygen saturation in frozen mouse tissues with confocal Raman cryomicroscopy

Terada

Ohno

Saitoh

et al. 2008

Journal of Structural Biology

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“…As such, carbohydrates and carbohydrate-derived polymers are often used for surface coating of metal nanoparticles as they can mimic glycoproteins in the biological systems. In the biomedical fields, they have been applied in molecular recognition processes, drug and gene delivery systems, surface modifiers, responsive hydrogels, stationary phases and treatment of diseases [16]. Carbohydrates and carbohydrate-derived polymers at the cell surface can involve in numerous biological functions such as adhesion, cell growth regulation, cancer cell metastasis and inflammation.…”

Section: Introductionmentioning

confidence: 99%