For more than a century, smoke explosions have been documented in the fire research literature. Yet even with this long history, smoke explosions have received very little attention in the fire research community. The few review articles on unexplained explosions (overpressure events) have adopted the conventional names of smoke explosions, backdraft, smoke gas explosions or rapid fire progression. Anecdotal evidence from firefighters have shown a number of overpressure events that cannot be explained as a gas leak or flammable liquids ignition. In this study, experiments were conducted in a plywood lined compartment with a timber crib as a sustained fire source and the ignition source. The compartment had a single vent that was open for the entire time. After an extended period of burning, the flames detached from the crib, traveled around the compartment, and finally self-extinguished. Sometime after the flames self-extinguished, the compartment erupted in flames culminating in a large horizontal flame projecting more than 2 m from the vent opening. In this study, a consistent cycle that leads to an overpressure event has been identified. A total of 29 overpressure events were created in 13 experiments with many experiments experiencing multiple overpressure events. Gas species, compartment temperatures, vent velocities, and compartment pressure were all recorded during the experiments. Conditions in the compartment immediately prior to the overpressure event are reported. Having demonstrated that an overpressure event within a combustible compartment can be reproduced, future research is recommended to better quantify the conditions leading to an overpressure event.