Multilayer insulation blankets are used in various sizes for thermal control of space systems. These multilayer insulation blankets are processed, usually by being seamed and patched. It is qualitatively understood that the thermal performance of small size multilayer insulation is more or less deteriorated. The effects of size of space use multilayer insulation blankets on thermal performance are known qualitatively, but not quantitatively. In this study, the thermal performance of limited size multilayer insulation blankets was measured by using the boil-off calorimeter method with liquid nitrogen. The temperature distribution on a rectangular multilayer insulation was also measured in order to investigate the nonuniformity of the local heat flux across the rectangular multilayer insulation. Thermal performance declines with the decrease of multilayer insulation area. This is because the local heat flux drastically increases in the hem region and the gap between the edge of blanket and base plate. Based on these measurement results, an equation to predict the thermal performance of multilayer insulation blankets of limited size was proposed. Nomenclature A = area, m 2 C = proportional constant C H = proportional constant in Eq. (11), W m −1 C L = constant of hem effect, W m −1 d = diameter, m G = evaporation rate of LN 2 , kg s −1 fN b ; t = function of multilayer insulation layer density, W m −2 h L = latent heat of evaporation, J kg −1 L = total hem length, m N b = layer number of multilayer insulation blanket, -Q = amount of heat, W q = heat flux, W m −2 T = temperature, K t = thickness, m x = distance from processed hem, m ε = emissivity,ρ = density, kg m −3 σ = Stefan-Boltzmann constant, W m −2 K −4 Subscripts B = boil-off tank or base plate BV = direct path from vacuum chamber to boil-off tank C-MLI = control multilayer insulation blanket, masking multilayer insulation blanket eff = effective value G = gap g = vapor Hem = hem of multilayer insulation blanket l = liquid MLI = outermost surface of multilayer insulation, test multilayer insulation MLI-B = bulk area of multilayer insulation, nonprocessed area of multilayer insulation N = number of layers, number of test multilayer insulation n = number of control multilayer insulation blankets S = outermost surface of multilayer insulation S0 ∼ S30 = name of multilayer insulation in Table 3 Total = total heat into boil-off tank, experimentally measured from the evaporation rate V = vacuum chamber