Invitro Assessment of Antimicrobial and Antioxidant Activity of Bioactive Compounds from Marine Algae

Rubavathi, S.; Ramya, M.

doi:10.20546/ijcmas.2016.507.026

Cited by 7 publications

(3 citation statements)

References 17 publications

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“…1,1-diphenyl-2 picryl hydrazyl (DPPH) radical scavenging activity was used for evaluating the radical scavenging activity according to the established protocol 10 . Extracts solution of 20, 40, 60, 80 and 100 µg/ml were prepared using their respective solvents.…”

Section: Dpph Assay Free Radical Scavenging Activitymentioning

confidence: 99%

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Studies on Antioxidant and Anti-obesity Activity of Salvia hispanica (Chia) Seeds Extracts

Rubavathi¹,

Ganesan²,

Sangeetha³

et al. 2020

J. Drug Delivery Ther.

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Obesity is a condition in which large amount of fat is stored in adipose tissue. Obesity is the greatest risk for many diseases like coronary heart disease, type 2 diabetes millions associated with insulin resistance, arthritis disorder, hypertension and cancers. Currently, the available drugs for obesity have been associated with number of side effects when compared with allopathic drugs. Salvia hispanica was one of the member of Lamiaceae family, collected to study the antiobesity activity. Extraction of Salvia hispanica using different solvents was done and tested for the presence of phytochemical constituents and the antimicrobial activity was monitored to evaluate the zone of inhibition. Further, antioxidant potential activity such as DPPH, FRAP and H2O2 assay was studied. Percentage of inhibition of Salvia hispanica was calculated and was observed as in capturing the free radicals present in the body. The surface and cross-sectional morphology Salvia hispanica extract nanoparticles was examined by using SEM. High ALA content make chia a perfect as it is associated with lower incidence of Cardiovascular diseases. This metabolic syndrome is mediated by inflammatory pathways. Hence, the in vitro activity of anti-inflammatory assay was performed by inhibition of albumin denaturation and anti-obesity activity was performed by lipase inhibition assay. Thus the result indicates that the seed extracts of Salvia hispanica possess antiobesity activity. Keywords: Salvia hispanica, anti-obesity, cholesterol, Antioxidant, lipase inhibition

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Section: Dpph Assay Free Radical Scavenging Activitymentioning

confidence: 99%

“…The ability of seed extracts to scavenge hydrogen peroxide can be estimated 10 . A solution of hydrogen peroxide (40mM) is prepared in phosphate buffer (50mM pH 7.4).…”

Section: Hydrogen Peroxide Scavenging Activitymentioning

confidence: 99%

Studies on Antioxidant and Anti-obesity Activity of Salvia hispanica (Chia) Seeds Extracts

Rubavathi¹,

Ganesan²,

Sangeetha³

et al. 2020

J. Drug Delivery Ther.

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“…Recently, they have widely been investigated due to their chemical and biological activities. 5 Polysaccharides present a large diversity of structures attributable to their variety in composition, substitutions and glycosidic bonds. Polysaccharides isolated from plants, fungi, yeasts and algae have attracted considerable attention for their biological activities in biochemistry and medicine.…”

Section: Introductionmentioning

confidence: 99%

Antimicrobial, antioxidant, cytotoxic and anticholinesterase activities of water-soluble polysaccharides extracted from microalgae Isochrysis galbana and Nannochloropsis oculata

et al. 2017

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The present work is carried out to evaluate potential applications of aqueous extracts of two microalgae Isochrysis galbana (PEA) and Nannochloropsis oculata (PEB) containing mainly polysaccharides. The monosaccharide composition of microalgal extracts was determined. GC-MS analyses after derivatization show that glucose is the major compound in both microalgae PEA (56.88 %) and PEB (68.23 %). Mannitol (38.8 %) and inositol (20.32 %) are respectively the second major compounds in PEA and PEB. Silylation of monosaccharides allows the determination of sorbitol that attained 3.38 % in PEB. The determination of antioxidant, antimicrobial and cytotoxic properties were also analyzed. Antioxidant activity was evaluated from the DPPH scavenging activity. PEA and PEB show a concentration dependent DPPH·radical scavenging activity. At concentration of 10 mg/mL, both PEA and PEB exhibit an antioxidant activity of 41.45 and 59.07 %, respectively. PEB and PEA are able to inhibit the growth of Gram-negative bacteria, Grampositive bacteria and three Candida species. Cytotoxic activity was evaluated on human HeLa cervical cancer cells. HeLa cell proliferation was totally inhibited after treatment with PEA and PEB (1 mg/mL) and the inhibition was dose dependent (from 0.031 to 1 mg/mL). Their anticholinesterase activity was also investigated against butyrylcholinesterase enzymes. These polysaccharides possess interesting antimicrobial, anticancer and anticholinesterase activities that could represent an additional value for these microalgal products.

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Antioxidant and Antibacterial Activities of Polysaccharides

Mohan¹,

Thirupathi²

2021

Polysaccharides of Microbial Origin

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Invitro Assessment of Antimicrobial and Antioxidant Activity of Bioactive Compounds from Marine Algae

Cited by 7 publications

References 17 publications

Studies on Antioxidant and Anti-obesity Activity of Salvia hispanica (Chia) Seeds Extracts

Studies on Antioxidant and Anti-obesity Activity of Salvia hispanica (Chia) Seeds Extracts

Antimicrobial, antioxidant, cytotoxic and anticholinesterase activities of water-soluble polysaccharides extracted from microalgae Isochrysis galbana and Nannochloropsis oculata

Antioxidant and Antibacterial Activities of Polysaccharides

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