Iodid schützt Bindehautzellen vor der Schädigung durch UV-Licht

Schmut, O.; Rieger, G.; Faulborn, J.; Winkler, Rudolf; Spitzenberger, Helga; Trummer, Gabriele

doi:10.1007/bf03162806

Cited by 6 publications

(6 citation statements)

References 20 publications

(10 reference statements)

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“…There are several other studies confirming the important role of iodide as a potent antioxidative scavenger of free radicals [31,[57][58][59][60][61][62][63] The high levels of iodide excretion seen in the treatment groups A, O and OA indicate the enlarged incorporation of iodine in all treated persons. The determination of total iodine excretion in urine is a generally accepted method to estimate the iodine supply of the body.…”

Section: Discussionmentioning

confidence: 85%

“…The significant improvement of the antioxidative protective capacity of the tear fluid by iodide iontophoresis in Bad Hall/ Austria is certainly an essential expansion of the treatment of dry eye syndrome, especially in cases with oxidative stress to the ocular surface [5,9,21,31,32,54,57,61,64] Further investigations are needed to elucidate iodine effects on other factors of dry eye disorders, for instance inflammation, which is another important finding in dry eye syndrome.…”

Section: Discussionmentioning

confidence: 99%

“…Iodide further protects hyaluronate in the tear fluid and also conjunctival cells of the ocular surface against ultraviolet B light-induced oxidative degradation [31].…”

Section: Discussionmentioning

confidence: 99%

“…Several studies have shown that considerable amounts of iodide can be transferred into all ocular tissues, especially to the anterior segment, using iontophoresis [24,[27][28][29][30], and could improve the antioxidative potential of the tear fluid when applied in this way [20,[31][32][33].…”

Section: Introductionmentioning

confidence: 99%

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The effect of iodide iontophoresis on the antioxidative capacity of the tear fluid

Rieger¹,

Klieber²,

Schimetta

et al. 2010

Graefes Arch Clin Exp Ophthalmol

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Section: Discussionmentioning

confidence: 85%

Section: Discussionmentioning

confidence: 99%

“…Iodide further protects hyaluronate in the tear fluid and also conjunctival cells of the ocular surface against ultraviolet B light-induced oxidative degradation [31].…”

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

The effect of iodide iontophoresis on the antioxidative capacity of the tear fluid

Rieger¹,

Klieber²,

Schimetta

et al. 2010

Graefes Arch Clin Exp Ophthalmol

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“…Die Wirkung von Iodid als Radikalfinger wurde vor kurzer Zeit auch dadurch nachgewiesen, dass Traneninhaltsstoffe [10] and auch Bindehautzellen [11] durch Iodid vor dem Angriff durch UV-Licht bzw. Ozon geschutzt werden konnten.…”

Section: Diskussionunclassified

Iodid schützt Hyaluronat vor oxidativem Stress

Schmut

Rieger²,

Winkler³

et al. 2004

Spektrum Augeheilkd

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Zusammenfassung. Hintergrund: H202 and daraus gebildete freie Radikale sind fir oxidativ bedingte Schaden verantwortlich. Es wurde untersucht, ob Iodid H 202 abbauen kann and somit einen Schutz vor oxidativem Stress darstellt. Material and Methode.' Die Abnahme der Konzentration von H202 in physiologischen Pufferlosungen nach IodidZusatz wurde durch Titration mit KMnO; Losungen bestimmt. Viskosimetrisch konnte die schutzende Wirkung von Iodid auf Hyaluronatlosungen vor dem oxidativen Abbau durch H202 gemessen werden. Resultate: Mikromolare Mengen von Iodid konnen die Konzentration von H202 in physiologischen Losungen rasch herabsetzen. Iodid besitzt die Fahigkeit, Hyaluronat vor der Depolymerisation durch H 202 zu schutzen. Schlussfolgerung: Die schi tzende Wirkung von Iodid vor H202 induziertem, oxidativem Stress kann unter anderem fir die positive Wirkung verantwortlich gemacht werden, die Bespruhungen and Iontophorese mit Iodsole, wie sie in Bad Hall (Oberosterreich) durchgefiihrt werden, am vorderen Augenabschnitt bewirken. Schlasselworter: Iodid, Schutz, oxidativer Stress, Wasserstoffperoxid (H2O2).Iodide protects hyaluronate from oxidative stress Summary. Background: H2O2 and free radicals are responsible for damaging reactions by oxidative stress. It was investigated whether iodide can destroy H 2 O2 and a protection against oxidative stress can be obtained by this reaction.Materials and methods: The decrease of H 2O2 concentrations in physiological buffer solutions by addition of iodide was determined by titration with KMnO4. By viscometry the protecting activity of iodide on hyaluronate solutions against oxidative degradation by H 2O2 was measured.Results: Micromolar amounts of iodide can decrease the H202 concentration in physiological solutions within a short time. Iodide has the capability to protect hyaluronate from depolymerization by H202 .Conclusions: The protecting activity of iodide from H202-induced oxidative stress may be responsible for the positive effect on the anterior part of the eye by sprays and iontophoresis with iodide brine as performed in Bad Hall (Upper Austria).

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Bäder- und Klimaheilkunde

Winkler¹,

Abel²

2003

Naturheilverfahren

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Iodid schützt Bindehautzellen vor der Schädigung durch UV-Licht

Cited by 6 publications

References 20 publications

The effect of iodide iontophoresis on the antioxidative capacity of the tear fluid

The effect of iodide iontophoresis on the antioxidative capacity of the tear fluid

Iodid schützt Hyaluronat vor oxidativem Stress

Bäder- und Klimaheilkunde

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