Ion-selective electrodes for determination of fluoxetine in capsules and in biological fluids

Hussien, Emad Mohamed; Abdel-Gawad, F. M.; Issa, Y. M.

doi:10.1016/j.bej.2010.10.015

Cited by 22 publications

(15 citation statements)

References 32 publications

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“…Among these methods are spectrophotometry [5][6][7][8], capillary electrophoresis [9][10][11], high-performance liquid chromatography (HPLC) [12,13], gas chromatography-mass spectrometry technique [14,15], fluorimetry [16], voltammetry [17][18][19][20] and potentiometry [21][22][23].…”

Section: Introductionmentioning

confidence: 99%

Imprinted Polymeric Beads-Based Screen-Printed Potentiometric Platforms Modified with Multi-Walled Carbon Nanotubes (MWCNTs) for Selective Recognition of Fluoxetine

et al. 2020

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Herein, we present a new validated potentiometric method for fluoxetine (FLX) drug monitoring. The method is based on the integration of molecular imprinting polymer (MIP) beads as sensory elements with modified screen-printed solid contact ion-selective electrodes (ISEs). A multi-walled carbon nanotube (MWCNT) was used as a nanomaterial for the ion-to-electron transduction process. The prepared MIP beads depend on the use of acrylamide (AAm) and ethylene glycol dimethacrylic acid (EGDMA) as a functional monomer and cross-linker, respectively. The sensor revealed a stable response with a Nernstian slope of 58.9 ± 0.2 mV/decade and a detection limit of 2.1 × 10−6 mol/L in 10 mmol/L acetate buffer of pH 4.5. The presented miniaturized sensors revealed good selectivity towards FLX over many organic and inorganic cations, as well as some additives encountered in the pharmaceutical preparations. Repeatability, reproducibility and stability have been studied to evaluate the analytical features of the presented sensors. These sensors were successfully applied for FLX assessment in different pharmaceutical formulations collected from the Egyptian local market. The obtained results agreed well with the acceptable recovery percentage and were better than those obtained by other previously reported routine methods.

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Section: Introductionmentioning

confidence: 99%

Imprinted Polymeric Beads-Based Screen-Printed Potentiometric Platforms Modified with Multi-Walled Carbon Nanotubes (MWCNTs) for Selective Recognition of Fluoxetine

et al. 2020

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“…Considering these merits, ISEs are getting more attention as routine tools of chemical analysis in industry, clinical and environmental analyses. [22][23][24][25][26] Coated-wire ion-selective electrodes that were employed to overcome the problems associated with conventional ISE's 27,28 still suffer some shortcomings such as giving unreliable measurements due to the fluctuation of the electric potential. 29 New measures must be introduced to the working electrodes to alleviate or eliminate these effects and carbon-paste electrodes (CPE's) 30 appear to be suitable alternatives.…”

Section: Introductionmentioning

confidence: 99%

Determination of Atomoxetine Hydrochloride in Biological Fluids Using Potentiometric Carbon Paste Electrode Modified by TiO2 Nanoparticles

Shawish

Saadeh

Tamous

et al. 2018

ACSi

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Endeavors to improve the limit of detection for atomoxetine-selective electrode were documented. Simple potentiometric carbon paste electrodes (CPEs) based on atomoxetine-derivatized with tetraphenylborate (ATM-TPB) or phosphotungstic acid (ATM-PTA) as ion-pairs decorated with TiO 2 nanoparticles and sodium tetraphenylborate (Na-TPB) as additives were most useful. Parameters affecting the performance of the electrodes were investigated, such as paste composition, type of plasticizers, kind of electroactive materials and interfering species. The electrodes were notable for bringing down the detection limit to 8.0 × 10-7 M and 9.2 × 10-7 M, wide linear ranges 1.1 × 10-6-1.0 × 10-2 M and 1.75 × 10-6-1.00 × 10-2 M, slope 58.7 ± 0.5 mV/decade and 67.2 ± 0.8 mV/decade, respectively. Importantly, the potential reading became more stable and rapidly attained in the presence of additives. The selectivity for the drug over other species such as inorganic and organic cations, as well as different excipients that are likely incorporated in pharmaceutical preparations was high making their effect negligible on the response of the electrodes. The sensors, as indicator electrodes, were successfully applied for determination of the drug in pharmaceutical preparation, urine and serum with good accuracy, excellent recovery and efficiency.

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“…Therefore, developing a very sensitive analytical method for the determination of FLX is of great importance (4). Several methods have been reported for the quantitation of FLX in various samples including capillary electrophoresis (5), nuclear magnetic resonance spectrometry (6), chromatography (7)(8)(9), chromatography-mass spectrometry (4,10,11), electrochemical methods (12,13), spectrophotometry (14)(15)(16) and spectrofluorimetry (2,17,18). Many of these methods have some major drawbacks such as lack of selectivity, tedious extraction procedures and time-consuming procedures.…”

Section: Introductionmentioning

confidence: 99%

Determination of fluoxetine in pharmaceutical and biological samples based on the silver nanoparticle enhanced fluorescence of fluoxetine–terbium complex

Lotfi

Manzoori

2016

Luminescence

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In this study, a simple and sensitive spectrofluorimetric method is presented for the determination of fluoxetine based on the enhancing effect of silver nanoparticles (AgNPs) on the terbium-fluoxetine fluorescence emission. The AgNPs were prepared by a simple reduction method and characterized by UV-Vis spectroscopy and transmission electron microscopy. It was indicated that these AgNPs have a remarkable amplifying effect on the terbium-sensitized fluorescence of fluoxetine. The effects of various parameters such as AgNP and Tb concentration and the pH of the media were investigated. Under obtained optimal conditions, the fluorescence intensity of the terbium-fluoxetine-AgNP system was enhanced linearly by increasing the concentration of fluoxetine in the range of 0.008 to 19 mg/L. The limit of detection (b + 3s) was 8.3 × 10 mg/L. The interference effects of common species found in real samples were also studied. The method had good linearity, recovery, reproducibility and sensitivity, and was satisfactorily applied for the determination of fluoxetine in tablet formulations, human urine and plasma samples. Copyright © 2016 John Wiley & Sons, Ltd.

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Ion-selective electrodes for determination of fluoxetine in capsules and in biological fluids

Cited by 22 publications

References 32 publications

Imprinted Polymeric Beads-Based Screen-Printed Potentiometric Platforms Modified with Multi-Walled Carbon Nanotubes (MWCNTs) for Selective Recognition of Fluoxetine

Imprinted Polymeric Beads-Based Screen-Printed Potentiometric Platforms Modified with Multi-Walled Carbon Nanotubes (MWCNTs) for Selective Recognition of Fluoxetine

Determination of Atomoxetine Hydrochloride in Biological Fluids Using Potentiometric Carbon Paste Electrode Modified by TiO2 Nanoparticles

Determination of fluoxetine in pharmaceutical and biological samples based on the silver nanoparticle enhanced fluorescence of fluoxetine–terbium complex

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