Ion-selective membrane electrodes for the determination of pyrantel with low protein interference

Adsorption of pyrantel pamoate on mercury from aqueous solutions: Studies by stripping voltammetry

“…HPLC was also applied to the analysis of pyrantel pamoate in human plasme [23,24] using UV detector. Potentiometric determination of pyrantel pamoate has also been reported [25] using ion selective electrodes and detection limit of 1-2 lg mL À1 of the drug has been claimed. But, the proposed method has a potential of a good analytical alternative in comparison to spectrophotometric and chromatographic methods for determining pyrantel pamoate in biological media and pharmaceutical formulations and it can be adopted for pharmacokinetic studies as well as for quality control laboratories studies.…”

“…ER 4008R) labeled to contain 250 mg pyrantel pamoate per tablet were obtained from commercial sources. Urine samples were obtained from healthy volunteers (five males, 25-35 year old volunteers) and a pool of these was used. Samples were kept frozen until assay.…”

Selective ketamine recognition based on membrane potential changes induced by a hybrid organic/inorganic supramolecular assembly

“…Indeed, the selectivity of cation exchanger based sensors is governed by the relative lipophilicity of the target and interfering ions as this inuences their abilities to form complexes with the anionic site in the membrane. 40 Importantly, the remarkable selectivity coefficients possessed by PM-CE based sensors with respect to morphine, codeine, ephedrine, norephedrine and dextromethorphan is, rst of all, interesting from a practical point of view since it opens up the possibility of assaying KT in illicit market samples, particularly since KT is a part of poly-substance use scenarios as mentioned earlier.…”

Polymeric Membrane Sensors for the Selective Determination of Dextromethorphan in Pharmaceutical Preparations

“…This can arise from the fact that the selectivity is governed by the relative lipophilicity of the target, and interfering ions as this influences their ability to form complexes with the anionic site in the membrane. 38 Morphine, codeine and ethylmorphine possess higher hydrophilicity; low lipophilicity, as compared to DXM, is presumably due to the presence of an OH hydrophilic group at position 6 in their backbones. Also, the DXM sensors are highly discriminatory against ephedrine and norephedrine, which sometimes added to antitussive drugs.…”