Ionic Liquid-Based Microwave-Assisted Extraction of Flavonoids from Bauhinia championii (Benth.) Benth.

Xu, Wei; Chu, Kedan; Li, Huang; Zhang, Yuqin; Zheng, Haiyin; Chen, Ruilan; Chen, Lidian

doi:10.3390/molecules171214323

Cited by 68 publications

(60 citation statements)

References 19 publications

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“…Compared with the traditional heat-reflux extraction (CHRE) and the conventional MAE, IL-MAE possesses the ability to yield a higher extraction in a shorter time. (Xu et al, 2012) Extraction of lipids from microalgae great opportunity in the halal market through producing halal certified enzymes and exploring substitutes to animal derived enzymes appropriate for halal food industry (Ermis, 2017). Some enzymes that are required to process food such as lactase for processing milk into lactose-free milk do not pose an issue if they are generated form GRAS microorganisms.…”

Section: ([Bmim] Br)mentioning

confidence: 99%

Ionic liquids: promising solvents for halal industry

Elgharbawy¹,

Azmi²,

Salleh³

2020

Food Res.

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Replacement of volatile organic solvents with ionic liquids (ILs) in industrial applications is a concerned matter and a trending approach. ILs became the choice of solvents due to their merits such as low melting points (<100°C) and insignificant vapor pressure. Despite being expansively investigated, ILs have not been intensively reviewed as eco-friendly solvents for the halal industry, which is the concept of this mini review. ILs have been used as surfactants, extractants for the purification of biomolecules, stabilizers for enzymes and in biosensors applications. Regardless of the lack of data on the toxicity of food products with ILs residues, low doses of ILs in in vitro tests did not lead to cell damage. Moreover, several ILs have stabilizing effects on biomolecules such as enzymes and proteins. Thus, new applications of ILs in the halal industry are feasible within the concept of halalan tayyiban (lawful and safe, good, wholesome).

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Section: ([Bmim] Br)mentioning

confidence: 99%

Ionic liquids: promising solvents for halal industry

Elgharbawy¹,

Azmi²,

Salleh³

2020

Food Res.

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“…[28][29][30][31] Briefly, a 3 g sample was extracted using ionic liquid based microwaveassisted extraction with [BMIM] Br and [BMIM] Cl as a solvent. The experiments performed at several combination such us ionic liquid concentration (0.6, 0.8, 1, 1.2, and 1.4 mol/L), ratio liquids/solid (8, 10, 12,14, and 16 ml/g), microwave power (10%,30%, 50%, 70%, and 100%), and extraction time (2, 3, 4, 5, and 6 minutes) using Design Expert 10 (STATEASE-USA).…”

Section: Non-conventional Extraction Methodsmentioning

confidence: 99%

Application of Ionic Liquid based Microwave-Assisted Extraction of the Secondary Metabolite from Peperomia pellucida (L) Kunth

Ahmad

Yanuar²,

Mulia³

et al. 2017

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Introduction: An ionic liquid (ILs) is a new alternative solvent (containing cations and anions) has the physical and specific solutions properties, and also had proven to be a promising substituent of conventional organic solvents are flammable, volatile and toxic in various processes. The ILS application in separating the secondary metabolites compound from Peperomia pellucida (L) Kunth herbaceous can be carried out using microwaveassisted extraction method (MAE). Objective: The aim of this study was to investigate the effect of ionic liquid based microwave-assisted extraction method for attracting the secondary metabolites compound from P. pellucida compared with a conventional solvent for the enrichment of secondary metabolites (especially polyphenols group) and their HPTLC fingerprinting profile. Methods: The herb dried powder extracted by microwave-assisted extraction using an ionic liquid such us 1-Butyl-3-methylimidazolium chloride ([BMIM]Cl), 1-Butyl-3-methylimidazolium Bromide ([BMIM]Br). The obtained extract solution was partitioned using an organic solvent; the extract was evaporated to obtain a dry extract and determination the HPTLC fingerprinting profile. Results: Based on the research results was obtained from the various types of solvents there are differences in the extraction of secondary metabolite.

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“…Moreover, to the best of our knowledge, IL-UAE has only been explored in the extraction of isoflavonoids from the roots of B. chinensis. The aim of this study is to develop a rapid, effective, and environmentally friendly IL-based ultrasound-assisted approach for the extraction of isoflavonoids from the roots of B. chinensis [19,20]. Using ultrafiltration LC-MS and 1 H and 13 C NMR spectroscopy, we screened and identified αglucosidase inhibitors ( Fig.…”

Section: Introductionmentioning

confidence: 99%

Ionic‐liquid‐based ultrasound‐assisted extraction of isoflavones from Belamcanda chinensis and subsequent screening and isolation of potential α‐glucosidase inhibitors by ultrafiltration and semipreparative high‐performance liquid chromatography

Huang

et al. 2017

J of Separation Science

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The separation of a compound of interest from its structurally similar homologues to produce high-purity natural products is a challenging problem. This work proposes a novel method for the separation of iristectorigenin A from its structurally similar homologues by ionic-liquid-based ultrasound-assisted extraction and the subsequent screening and isolation of potential α-glucosidase inhibitors via ultrafiltration and semipreparative high-performance liquid chromatography. Ionic-liquid-based ultrasound-assisted extraction was successfully applied to the extraction of tectorigenin, iristectorigenin A, irigenin, and irisflorentin from Belamcanda chinensis. The optimum conditions for the efficient extraction of isoflavones were determined as 1.0 M 1-ethyl-3-methylimidazolium tetrafluoroborate with extraction time of 30 min and a solvent to solid ratio of 30 mL/g. Ultrafiltration with liquid chromatography and mass spectrometry was applied to screen and identify α-glucosidase inhibitors from B. chinensis, followed by the application of semipreparative high-performance liquid chromatography to separate and isolate the active constituents. Four major compounds including tectorigenin, iristectorigenin A, irigenin, and irisflorentin were screened and identified as α-glucosidase inhibitors, and then the four active compounds abovementioned were subsequently isolated by semipreparative high-performance liquid chromatography (99.89, 88.97, 99.79, and 99.97% purity, respectively). The results demonstrate that ionic liquid extraction can be successfully applied to the extraction of isoflavones from B. chinensis.

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Ionic Liquid-Based Microwave-Assisted Extraction of Flavonoids from Bauhinia championii (Benth.) Benth.

Cited by 68 publications

References 19 publications

Ionic liquids: promising solvents for halal industry

Ionic liquids: promising solvents for halal industry

Application of Ionic Liquid based Microwave-Assisted Extraction of the Secondary Metabolite from Peperomia pellucida (L) Kunth

Ionic‐liquid‐based ultrasound‐assisted extraction of isoflavones from Belamcanda chinensis and subsequent screening and isolation of potential α‐glucosidase inhibitors by ultrafiltration and semipreparative high‐performance liquid chromatography

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