Ionic Liquids for the Synthesis and Design of Hybrid Biomaterials and Interfaces

Pereira, Rui F. P.; Zehbe, Kerstin; Krüger, Stefanie; Silva, Maria Manuela; Salama, Ahmed; Hesemann, Peter; Bermúdez, V. de Zea; Taubert, Andreas

doi:10.1002/9783527807130.ch13

Cited by 2 publications

(5 citation statements)

References 231 publications

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“…Motivated by the extraordinary versatility offered by ILs, we report in the present study a set of radically new mesoporous silk fibroin (SF)/silica hybrid materials prepared, for the first time, by means of a one-pot, soft sol–gel synthesis procedure, in which all of the precursor compounds co-exist in the same reaction medium. This new method relies on the following precursors: a Si source (tetramethylorthosilicate, TMOS), an acid or a base exerting the role of catalysts, and the IL 1-butyl-3-methylimidazolium chloride ([Bmim][Cl]) acting at the same time as adequate solvent for the SF 79 and as template for the formation of the final mesoporous hybrid materials. It is noteworthy that the synthesis of the MBG/silk scaffolds discussed above involved a two-step procedure and required several compulsory compounds.…”

Section: Introductionmentioning

confidence: 99%

Ionic Liquid-Assisted Synthesis of Mesoporous Silk Fibroin/Silica Hybrids for Biomedical Applications

et al. 2018

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New mesoporous silk fibroin (SF)/silica hybrids were processed via a one-pot soft and energy-efficient sol–gel chemistry and self-assembly from a silica precursor, an acidic or basic catalyst, and the ionic liquid 1-butyl-3-methylimidazolium chloride, acting as both solvent and mesoporosity-inducer. The as-prepared materials were obtained as slightly transparent-opaque, amorphous monoliths, easily transformed into powders, and stable up to ca. 300 °C. Structural data suggest the formation of a hexagonal mesostructure with low range order and apparent surface areas, pore volumes, and pore radii of 205–263 m2 g–1, 0.16–0.19 cm3 g–1, and 1.2–1.6 nm, respectively. In all samples, the dominating conformation of the SF chains is the β-sheet. Cytotoxicity/bioactivity resazurin assays and fluorescence microscopy demonstrate the high viability of MC3T3 pre-osteoblasts to indirect (≥99 ± 9%) and direct (78 ± 2 to 99 ± 13%) contact with the SF/silica materials. Considering their properties and further improvements, these systems are promising candidates to be explored in bone tissue engineering. They also offer excellent prospects as electrolytes for solid-state electrochemical devices, in particular for fuel cells.

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Section: Introductionmentioning

confidence: 99%

Ionic Liquid-Assisted Synthesis of Mesoporous Silk Fibroin/Silica Hybrids for Biomedical Applications

et al. 2018

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“…Within the last twenty years, ILs and the so-called room temperature ILs (RTILs), namely ILs which are liquid at room temperature, have gained attention for their potential application in several chemical fields including their use as solvents and catalysts for chemical syntheses (Clarke et al 2018;Keaveney et al 2017), separation technologies, or electrochemistry (Pereira et al 2018). Noteworthy, ILs show unique properties such as high chemical and thermal stability (Maton et al 2013;Mezzetta et al 2019b), low vapor pressure, and no flammability (Singh and Savoy 2020;Welton 2018).…”

Section: Ionic Liquidsmentioning

confidence: 99%

“…Liebert and Heinze considered three paths for side reactions of imidazolium salts including the fairly high reactivity of the anion as a nucleophile, the (Pereira et al 2018) Cellulose abstraction of the C-2 proton of the 1,3-alkylimidazolium moiety, and ring-opening reactions (Liebert and Heinze 2008). They indicated that using C-2 alkyl substituted imidazolium ILs for the etherification of cellulose can decrease side reactions.…”

Section: Ionic Liquidsmentioning

confidence: 99%

“…The presence of ILs with sufficient solubility of cellulose opens new windows for its functionalization and processing and can basically change the current situation. However, the advantages offered by IL for the synthesis of cellulose-based composites and blends have only been partially exploited to date (Pereira et al 2018).…”

Section: Wet-spinningmentioning

confidence: 99%

“…Fig. 2 a Examples of common IL cations and anions, b Chemical structure of nontoxic anions(Pereira et al 2018) …”

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Cellulose-based fiber spinning processes using ionic liquids

et al. 2022

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Cellulose, a natural, renewable, and environment friendly biopolymer, has been considered as a sustainable feedstock in the near future. However, only 0.3% of cellulose is today processed since it is not soluble in conventional solvents due to the strong hydrogen bonding network and highly ordered structure. Hence, the search of effective and eco-friendly solvents for cellulose dissolution has been a key pillar for decades. In the recent years, ionic liquids (ILs) have been proposed as green solvents for cellulose and have been applied for the production of cellulose-based fibers. This review aims to focus the attention toward fiber spinning methods of cellulose based on ILs, as well as recent progress in cellulose dissolution using ILs. Moreover, the development of cellulosic fibers blended with other biopolymers, and cellulose composites are presented. Finally, different applications of cellulose fibers and composites are summarized and discussed.

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Ionic Liquids for the Synthesis and Design of Hybrid Biomaterials and Interfaces

Cited by 2 publications

References 231 publications

Ionic Liquid-Assisted Synthesis of Mesoporous Silk Fibroin/Silica Hybrids for Biomedical Applications

Ionic Liquid-Assisted Synthesis of Mesoporous Silk Fibroin/Silica Hybrids for Biomedical Applications

Cellulose-based fiber spinning processes using ionic liquids

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