Ionophores for Dairy Cattle: Current Status and Future Outlook

McGuffey, R.K.; Richardson, L. F.; Wilkinson, J. I. D.

doi:10.3168/jds.s0022-0302(01)70218-4

Cited by 300 publications

(303 citation statements)

References 84 publications

Supporting

Mentioning

224

Contrasting

Unclassified

Order By: Relevance

“…There were no significant treatment effects for plasma glucose concentration in any of the evaluated periods. Observed values are in agreement with those found in the literature for calves of similar age (Quigley and Bernard, 1992;Nussio et al, 2003a).Owing to the ruminal fermentation pattern modification, as a result of monensin supplementation, with higher propionate concentrations (McGuffey et al, 2001), a higher plasma glucose concentration was expected for calves fed starter containing the ionophore. Similarly, the direct supplementation of propionate via calcium propionate should have resulted in the same response, since propionate is the main glucose precursor in the liver (Bergman, 1990).…”

supporting

confidence: 90%

“…Owing to the ruminal fermentation pattern modification, as a result of monensin supplementation, with higher propionate concentrations (McGuffey et al, 2001), a higher plasma glucose concentration was expected for calves fed starter containing the ionophore. Similarly, the direct supplementation of propionate via calcium propionate should have resulted in the same response, since propionate is the main glucose precursor in the liver (Bergman, 1990).…”

Section: Resultsmentioning

confidence: 99%

“…These authors observed lower intakes of starter with monensin during the period after weaning, suggesting that the negative effect may occur when the animal presents the rumen partly developed. In addition, literature frequently shows the inhibitory effect of monensin on DM intake by adult animals (McGuffey et al, 2001). However, no control treatment was tested during this trial, since most commercial starters have monensin in their composition.…”

Section: Resultsmentioning

confidence: 99%

See 2 more Smart Citations

Performance and plasma metabolites of dairy calves fed starter containing sodium butyrate, calcium propionate or sodium monensin

Ferreira

Bittar

2011

Animal

View full text Add to dashboard Cite

This study was conducted to examine the influence of supplementation of sodium butyrate, sodium monensin or calcium propionate in a starter diet on the performance and selected plasma metabolites (plasma glucose, non-esterified fatty acids and b-hydroxybutyrate) of Holstein calves during pre-and post-weaning periods. Twenty-four newborn Holstein calves were housed in individual hutches until 10 weeks of life, receiving water free choice, and fed four liters of milk daily. Calves were blocked according to weight and date of birth, and allocated to one of the following treatments, according to the additive in the starter: (i) sodium butyrate (150 g/kg); (ii) sodium monensin (30 mg/kg); and (iii) calcium propionate (150 g/kg). During 10 weeks, calves received starter ad libitum, while coast cross hay (Cynodon dactylon (L.) pers.) was offered after weaning, which occurred at the 8th week of age. Weekly, calves were weighted and evaluated for body measurements. Blood samples were taken weekly after the fourth week of age, 2 hours after the morning feeding, for determination of plasma metabolites. No differences were observed among treatments for starter or hay intake, BW and daily gain of the animals. Mean concentrations of selected plasma metabolites were similar in calves fed a starter supplemented with sodium butyrate, sodium monensin and calcium propionate. There was significant reduction in the concentrations of plasma glucose as calves aged. The inclusion of sodium butyrate, calcium propionate or sodium monensin as additives in starter feeds resulted in equal animal performance, before and after weaning, suggesting that sodium monensin may be replaced by organic acid salts. Keywords: additives, early weaning, ionophores, ruminal development ImplicationsThis study was conducted to evaluate organic acid salts inclusion in calf starters as a replacement to the traditional use of ionophore, since these antibiotics were banned as growth promoters in the European Union. Since all commercial starters include ionophores, an alternative additive that could result in the same pattern of animal performance should be studied. The organic acid salts were chosen because they lack the antibiotic effect but could have beneficial effects on the rumen development processes. In addition, as seen in the non-ruminant industry, acidified feeds may have a beneficial effect on the health of the lower gastrointestinal tract. IntroductionCalf rumen development, crucial for the early weaning program, is strongly related to the intake of fermentable organic matter and the resulting short-chain fatty acids (SCFA; Greenwood et al., 1997). Ruminal metabolism studies have pointed out butyric and propionic acids as the main stimuli for rumen development and the maturation process , which suggests that additives that furnish higher SCFA concentrations or alter the rumen fermentation pattern may be used as a tool for reducing the milk feeding period.The inclusion of ionophores in ruminant diets has shown changes in the SCFA concentrations, mainl...

show abstract

supporting

confidence: 90%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Performance and plasma metabolites of dairy calves fed starter containing sodium butyrate, calcium propionate or sodium monensin

Ferreira

Bittar

2011

Animal

View full text Add to dashboard Cite

show abstract

“…Desta forma, este gasto de energia pode levar a redução no crescimento, reprodução e, muitas vezes, até a morte de determinado tipo de bactéria (McGUFFEY et al, 2001). …”

Section: Ionóforos Na Alimentação De Ruminantesunclassified

“…Bactérias gram-positivas não possuem esta membrana externa, estando susceptíveis as ações do ionóforo (McGUFFEY et al, 2001;IPHARRAGUERRE ;CLARK, 2003).…”

Section: Fermentação Ruminalunclassified

Desempenho produtivo e resíduos no leite de vacas suplementadas com monensina sódica nas rações

Santos¹

View full text Add to dashboard Cite

Agradeço, primeiramente a Deus, por tornar possível meus sonhos.Agradeço a minha família, por me apoiarem e incentivarem. Pela sabedoria a que me guiaram e continuam guiando pelos caminhos da vida, sempre me ensinando o discernimento e conduzindo para caminhos certos. À empresa Tortuga pela concessão do auxílio à pesquisa que resultou na realização deste estudo.Ao meu orientador Prof. Dr. Francisco Palma Rennó, pela oportunidade de realização deste estudo, pela confiança em minha capacidade, pela sabedoria e ensinamentos. Pela competência, orientação, profissionalismo, paciência e dedicação. Por todas as conversas e críticas que foram muito produtivas em minha vida. Reconheço hoje o quanto cresci pessoalmente e profissionalmente e muito disso devo ao meu orientador, por ter me apoiado quando precisei e ter me repreendido quando estava errada. Afinal, errando é que se aprende e agradeço muito a oportunidade de ter feito parte de sua equipe.Ao Carlinhos, por todos os ensinamentos e ajuda indispensável para a realização do estudo.As grandes amigas Beatriz (Bixuka) e Ana Paula, por todo o companheirismo, dedicação, paciência, apoio e amizade. Por todas as horas de conversas, risadas, desabafos, desesperos e de alegrias. Obrigada por você fazer parte da minha vida. A vida nos tornou amigas e o coração nos tornou irmãs.Ao José Esler, por tornar possível esse estudo e suas análises. Pela ajuda e dedicação que foi imprescindível. Pelas horas de conselhos e conversas. Por ter se tornado um amigo tão especial.À amiga Esther por toda a paciência e amizade. Por ter me recebido tão bem aqui e sempre ter me ajudado.À amiga Lenita por todas as horas de conversa e conselhos, por sempre me apoiar e ajudar.À Cybele e Gabriella por em tão pouco tempo de convivência terem se tornado pessoas tão importantes em minha vida, sempre me apoiando e me ajudando. Houve efeito linear decrescente do consumo de matéria seca, matéria orgânica, proteína bruta, extrato etéreo, carboidratos totais, fibra detergente neutro, carboidratos não fibrosos e nutrientes digestíveis totais. Não houve diferença na digestibilidade aparente total da matéria seca e dos nutrientes em função das rações experimentais, excetuando-se a digestibilidade aparente total da proteína bruta e fibra detergente neutro, que foram observados efeitos linear crescente e decrescente, respectivamente. Não houve efeito das rações experimentais sobre os valores de pH ruminal. A suplementação com monensina sódica nas dietas resultou em alteração da proporção molar de propionato no líquido ruminal, além de diminuir a relação acetato:propionato. As rações contendo monensina sódica apresentaram maior proporção molar de propionato e menor de acetato em relação à ração controle, e, de forma semelhante, apresentaram menor relação acetato:propionato. Não houve efeito das dietas experimentais nas excreções diárias totais de urina, de alantoína e de acido úrico na urina, e de derivados de purinas totais. Não houve diferença na porcentagem de alantoína nos derivados de purina, das purinas abso...

show abstract

A novel fluorescent probe with large Stokes shift for the detection of viscosity changes and its imaging in living cells

et al. 2022

View full text Add to dashboard Cite

As an important cellular microenvironmental parameter, viscosity could reflect the status of living cells. Small molecular fluorescent probes are a vital tool to measure the change of viscosity in living cells. A novel fluorescence probe ZL-1 with a large Stokes shift (in methanol it reached to 153 nm and in glycerol it reached to 125 nm) and excellent sensitivity toward viscosity was developed. The sharp enhancement of the emission intensity for the probe ZL-1 from low viscous methanol to high viscous glycerol indicated that the probe ZL-1 could respond to the viscosity variations.Moreover, the probe ZL-1 has been successfully utilized to detect of the viscosity variations in living cells.

show abstract

Ionophores for Dairy Cattle: Current Status and Future Outlook

Cited by 300 publications

References 84 publications

Performance and plasma metabolites of dairy calves fed starter containing sodium butyrate, calcium propionate or sodium monensin

Performance and plasma metabolites of dairy calves fed starter containing sodium butyrate, calcium propionate or sodium monensin

Desempenho produtivo e resíduos no leite de vacas suplementadas com monensina sódica nas rações

A novel fluorescent probe with large Stokes shift for the detection of viscosity changes and its imaging in living cells

Contact Info

Product

Resources

About