Iontophoresis for palmoplantar hyperhidrosis

Kreyden, Oliver P

doi:10.1111/j.1473-2130.2004.00126.x

Cited by 32 publications

(41 citation statements)

References 13 publications

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“…Ayrıca bu bölgede iritasyon, yanma hissi ve yanık gibi yan etkiler sık görülmek-tedir (9,39). Bu nedenle iyontoforezin aksiller hiperhidroz tedavisinde kullanımı çok fazla önerilmemektedir (9).…”

Section: Endikasyonları Ve Etkinliğiunclassified

“…İyontoforez tedavisinde genel olarak direkt (galvanik) akım uygulanır (15,34,39). Ama bazı çalışmalarda alternatif akım da tek başına veya direkt akım ile birlikte kullanılmıştır (33,36).…”

Section: Tedavi Yöntemi Ve Protokolüunclassified

“…Derideki erozyon ve fissürler vazelin ile kapatılır (39). El ve/ veya ayaklar bileklerin hizasına kadar musluk suyu ile dolu iki ayrı plastik kaba yerleştirilir (39,46). Palmar ve/veya plantar bölgeler kabın tabanıyla tam temas etmelidir.…”

Section: Tedavi Yöntemi Ve Protokolüunclassified

“…Palmar ve/veya plantar bölgeler kabın tabanıyla tam temas etmelidir. Anot ve katot uçların her biri ayrı kaplara konur (39,52). Aynı kaba konulduğu zaman akımın tüm vücut yerine yalnızca su ile tedavi edilen bölge arasında dolaşacağı, dolayısıyla, tedavi için gerekli olan toplam seans sayısının artacağı ve daha yüksek akım şiddetine ihtiyaç olacağı bildirilmiştir (52).…”

Section: Tedavi Yöntemi Ve Protokolüunclassified

“…içinde yavaş yavaş artırılır (3,16,34). Hastanın herhangi bir rahatsızlık hissetmediği seviyede akım şiddeti sabitlenir (39). Her seans 20-30 dk.…”

Section: Tedavi Yöntemi Ve Protokolüunclassified

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Hyperhidrosis and Its Treatment: A Safe and Effective Alternative in the Treatment of Palmoplantar Hyperhidrosis, Iontophoresis

Özcan¹,

Güleç²

2011

Turk J Dermatol

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ÖzetPrimer hiperhidroz sebebi bilinmeyen, en sık palmar, plantar ve aksiller bölgede ortaya çıkan, çoğunlukla bilateral ve simetrik olan aşırı terleme ile karakterizedir. Etkilenen bireylerde fiziksel rahatsızlıklar ve psikososyal güçlüklere yol açtığı için etkin bir şekilde tedavi edilmelidir. Ancak, patofizyolojisinin tam olarak anlaşılmaması nedeniyle tedavisi zordur. Topikal ve sistemik ajanlar ile cerrahi ve cerrahi olmayan invaziv teknikler gibi çeşitli seçenekler bulunmaktadır. İyontoforez, iyonize maddelerin elektrik akımı aracılığıyla yüzey dokulara uygulanması işlemidir. Primer hiperhidrozda invaziv olmayan, güvenli, iyi tolere edilen, etkili ve uzun dönem yan etkiler ile kompansatuvar hiperhidroza neden olmayan bir tedavi yöntemidir. Şiddetli palmar ve/veya plantar hiperhidrozda ve topikal tedaviye yanıt vermeyen orta şiddetteki olgularda ilk tedavi seçeneği olarak önerilmektedir. Aksiller hiperhidrozda ise etkinliği düşüktür ve kullanımı pratik değildir. Zaman alıcı olması ve idame tedavisinin gerekliliği ise en önemli dezavantajlarıdır. Bu makalede, hiperhidroz ve başlıca tedavi seçenekleri, iyontoforezin primer hiperhidroz tedavisindeki endikasyonları, etki mekanizması, tedavi protokolü ile yöntemi, yan etkileri ve kontrendikasyonları derlenmiştir. AbstractPrimary hyperhidrosis is characterized by excessive sweating of unknown cause which most commonly involves the palms, soles, and axillae in a bilateral and symmetrical fashion. Since it leads to physical discomfort and psychosocial difficulties in the affected individuals, it should be treated effectively. However, treatment can be challenging as its pathophysiology is poorly understood. There are several treatment options, including topical or systemic medications and surgical or non-surgical invasive techniques. Iontophoresis is the introduction of ionized substances into the surface tissues by means of an electric current. It is a non-invasive, safe, well tolerated, and effective treatment method for primary hyperhidrosis without long-term adverse effects and compensatory hyperhidrosis. Iontophoresis is suggested as a first-line therapy in severe palmoplantar hyperhidrosis and second-line therapy in milder cases that are unresponsive to topical treatments. In axillary hyperhidrosis it is less effective and not practical to use. Being time consuming and requiring maintenance therapy are its most important disadvantages. In this article, hyperhidrosis and the principal treatment options, the indications of iontophoresis for the treatment of primary hyperhidrosis, its mechanism of action, treatment protocol and procedure, adverse effects, and contraindications are reviewed. (Turk J Dermatol 2011; 5: 5-12)

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Section: Endikasyonları Ve Etkinliğiunclassified

Section: Tedavi Yöntemi Ve Protokolüunclassified

“…içinde yavaş yavaş artırılır (3,16,34). Hastanın herhangi bir rahatsızlık hissetmediği seviyede akım şiddeti sabitlenir (39). Her seans 20-30 dk.…”

Section: Tedavi Yöntemi Ve Protokolüunclassified

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Hyperhidrosis and Its Treatment: A Safe and Effective Alternative in the Treatment of Palmoplantar Hyperhidrosis, Iontophoresis

Özcan¹,

Güleç²

2011

Turk J Dermatol

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Advancements in Skin‐Mediated Drug Delivery: Mechanisms, Techniques, and Applications

Lee,

Lim,

Kwak

et al. 2023

Adv Healthcare Materials

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Skin‐mediated drug delivery methods currently are receiving significant attention as a promising approach for the enhanced delivery of drugs through the skin. Skin‐mediated drug delivery offers the potential to overcome the limitations of traditional drug delivery methods, including oral administration and intravenous injection. The challenges associated with drug permeation through layers of skin, which act as a major barrier, are explored, and strategies to overcome these limitations are discussed in detail. This review categorizes skin‐mediated drug delivery methods based on the means of increasing drug permeation, and it provides a comprehensive overview of the mechanisms and techniques associated with these methods. In addition, recent advancements in the application of skin‐mediated drug delivery are presented. The review also outlines the limitations of ongoing research and suggests future perspectives of studies regarding the skin‐mediated delivery of drugs.

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Plasma Applications: A Dermatological View

Tiede

Hirschberg

Daeschlein

et al. 2014

Contrib. Plasma Phys.

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The ability to produce cold plasma at atmospheric pressure conditions was the basis for the rapid growth of plasma related application areas in biomedicine. Plasma comprises a multitude of active components such as charged particles, electric current, UV radiation, and reactive species which can act synergistically. The antiitch, antimicrobial, and anti‐inflammatory effect was already demonstrated in in vivo and in vitro experiments and until now no resistance of pathogens against plasma treatment was observed. The combination of the different active agents and their broad range of positive effects on various diseases, especially easily accessible skin diseases, render plasma quite attractive for applications in medicine. Hence, plasma medicine as an independent and promising medical field has been emerged recently. For medical applications two different types of cold plasma are suitable; indirect (plasma jet, plasma torch) and direct plasma sources (dielectric barrier discharge ‐ DBD). So far, no standards and norms are defined for any of these plasma sources. Also, no convenient criteria for standardization of the quality rating of plasma in the view of dermatological applications exist. Although various cold plasma studies have been performed the results are hardly comparable, as physical parameters of the plasma devices, experimental conditions, and organisms used vary greatly. Therefore, standardized risk analyses are necessary for the assessment of different plasma sources. In this review two plasma sources are described and possible risk factors are discussed to estimate the safety of plasma used as a therapeutic tool in dermatology. (© 2014 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)

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Iontophoresis for palmoplantar hyperhidrosis

Cited by 32 publications

References 13 publications

Hyperhidrosis and Its Treatment: A Safe and Effective Alternative in the Treatment of Palmoplantar Hyperhidrosis, Iontophoresis

Hyperhidrosis and Its Treatment: A Safe and Effective Alternative in the Treatment of Palmoplantar Hyperhidrosis, Iontophoresis

Advancements in Skin‐Mediated Drug Delivery: Mechanisms, Techniques, and Applications

Plasma Applications: A Dermatological View

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