With the rapid development of electronic technology, network technology and cloud computing technology, the current data is increasing in the way of mass, has entered the era of big data. Based on cloud computing clusters, this paper proposes a novel method of parallel implementation of multilayered neural networks based on Map-Reduce. Namely in order to meet the requirements of big data processing, this paper presents an efficient mapping scheme for a fully connected multi-layered neural network, which is trained by using error back propagation (BP) algorithm based on Map-Reduce on cloud computing clusters (MRBP). The batch-training (or epoch-training)