“…In this study, however, where the order of administering the tablets did not produce significantly different results, we have been unable to confirm their findings. In view of the considerable number of double-blind trials (Dewar et al, 1959;Snow and Anderson, 1959;Fife et al, 1960;Phear and Walker, 1960;Allanby et al, 1961;Murphy et al, 1961), in addition to this study, which have failed to confirm the value of the mono-amine oxidase inhibitors in the treatment of angina pectoris, it seems increasingly difficult to be convinced that earlier enthusiastic reports of improvement based on uncontrolled trials were not due to temporary changes in the mental outlook of the individual patients concerned or to natural variations in the symptoms of angina pectoris.…”