2022
DOI: 10.21203/rs.3.rs-2046024/v1
|View full text |Cite
Preprint
|
Sign up to set email alerts
|

IPSS-M has greater survival predictive accuracy compared with IPSS-R in persons ≥ 60 years with myelodysplastic syndromes

Abstract: There are considerable new data on mutation topography in persons with myelodysplastic syndromes (MDS). These data have been used to update conventional risk models such as the Revised International Prognostic Scoring System (IPSS-R). Whether the molecular IPSS (IPSS-M) which includes these data improves survival prediction accuracy is untested. To answer this question, we compared survival prediction accuracies of the IPSS-R and IPSS-M in 852 consecutive subjects with de novo MDS. Concordance statistics (C-st… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

0
1
0

Year Published

2024
2024
2024
2024

Publication Types

Select...
1

Relationship

0
1

Authors

Journals

citations
Cited by 1 publication
(1 citation statement)
references
References 33 publications
(35 reference statements)
0
1
0
Order By: Relevance
“…Based on clinical research, Bernard proposed a prognostic model for IPSS-M combined with genetic mutations [5] . After veri cation, Wu et al and Wan et al proposed that compared to IPSS-R, IPSS-M may be more accurate in predicting prognostic risk, which is signi cant for guiding personalized clinical treatment [6,7] . Genetic mutations have great potential in predicting the prognostic risk of MDS patients.…”
mentioning
confidence: 99%
“…Based on clinical research, Bernard proposed a prognostic model for IPSS-M combined with genetic mutations [5] . After veri cation, Wu et al and Wan et al proposed that compared to IPSS-R, IPSS-M may be more accurate in predicting prognostic risk, which is signi cant for guiding personalized clinical treatment [6,7] . Genetic mutations have great potential in predicting the prognostic risk of MDS patients.…”
mentioning
confidence: 99%