Summary Solar thermal power generation technology has great significance to alleviate global energy shortage and improve the environment. Solar energy must be stored to provide a continuous supply because of the intermittent and instability nature of solar energy. Thermochemical storage (TCS) is very attractive for high‐temperature heat storage in the solar power generation because of its high energy density and negligible heat loss. To further understand and develop TCS systems, comprehensive analyses and studies are very necessary. The basic principle and main components of a solar TCS system are described in this paper. Besides, recent progress and existing problems of several promising reaction systems are introduced. Further research directions are pointed out considering the technical, economic, and environmental issues that existed in the wide application of TCS. Copyright © 2014 John Wiley & Sons, Ltd.

Computational identification of transcription factor binding sites is an important research area of computational biology. Positional weight matrix (PWM) is a model to describe the sequence pattern of binding sites. Usually, transcription factor binding sites prediction methods based on PWMs require user-defined thresholds. The arbitrary threshold and also the relatively low specificity of the algorithm prevent the result of such an analysis from being properly interpreted. In this study, a method was developed to identify over-represented cis-elements with PWM-based similarity scores. Three sets of closely related promoters were analyzed, and only over- represented motifs with high PWM similarity scores were reported. The thresholds to evaluate the similarity scores to the PWMs of putative transcription factors binding sites can also be automatically determined during the analysis, which can also be used in further research with the same PWMs. The online program is available on the website: http://www.bioinfo.tsinghua.edu.cn/- zhengjsh/OTFBS/.

ZnO thin films with various thicknesses were prepared onto glass substrates by pulsed laser deposition. The crystallinity, microstructure and surface morphology of ZnO thin films were investigated by X-ray diffraction (XRD), scanning electron microscopy (SEM) and scanning probe microscopy (SPM). As the thickness of the films increased, the grain size and the surface roughness increased as well the tensile stress decreased. Also, to study the optical-electrical properties of the films, we tested the carrier concentration, mobility, resistivity, impedance spectroscopy and optical transmission spectra. The results showed that the carrier concentration gradually increased as the thickness increased from 20 to 106 nm, thereafter decreased as the thickness further increased to 216 nm. The main contribution to the conduction of the films with thickness from 20 to 106 nm gradually converted from grain boundaries to grains, and converted into grain boundaries again for the films with a thickness of 216 nm. As the thickness of the films decreased, it was found that the blue shift of absorption edge of optical transmission spectra. Effects of the thicknesses on the optical and electrical properties for ZnO films were related to their grain size, stress and carrier concentration.

Cancer as a large group of complex diseases is believed to result from the interactions of numerous genetic and environmental factors but may develop in people without any known genetic or environmental risks, suggesting the existence of other powerful factors to influence the carcinogenesis process. Much attention has been focused recently on particular members of the intestinal microbiota for their potential roles in promoting carcinogenesis. Here we report the identification and characterization of intestinal bacteria that exhibited potent anti-malignancy activities on a broad range of solid cancers and leukemia. We collected fecal specimens from healthy individuals of different age groups (preschool children and university students), inspected their effects on cancer cells, and obtained bacteria with potent anti-malignancy activities. The bacteria mostly belonged to Actinobacteria but also included lineages of other phyla such as Proteobacteria and Firmicutes. In animal cancer models, sterile culture supernatant from the bacteria highly effectively inhibited tumor growth. Remarkably, intra-tumor administration of the bacterial products prevented metastasis and even cleared cancer cells at remote locations from the tumor site. This work demonstrates the prevalent existence of potent malignancy-killers in the human intestinal microbiota, which may routinely clear malignant cells from the body before they form cancers.

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