Iridoids from Neopicrorhiza scrophulariiflora and Their Hepatoprotective Activities in Vitro

Constituintes químicos de Capraria biflora (Scrophulariaceae) e atividade larvicida de seu óleo essencial

“…A reação de acetilação e comparação com dados da literatura 17,18 permitiram a confirmação da proposta estrutural para a referida substância com sua respectiva estereoquímica, que foi identificada como a (1R,5S,6S,7R,8S,9S)-7-cloro-8-(hidroximetil) octa-hidrociclopenta[c]piran-1,10-oxira-5,6,8-triol (miopoclorina), já identificada anteriormente na espécie Myoporum bontioides e que está sendo reportada pela primeira vez em C. biflora, bem como seus derivados acetilados. …”

Sensitive HPLC–APCI–MS method for the determination of cyclovirobuxine D in human plasma

“…[1], is the active component of huangyangning tablet, which is widely used in China for the treatment of arrhythmias, angina pectoris and cardiac insufficiency [1,2]. CVB-D possesses the effect on preventing and treating arrhythmia [3,4]. It can significantly prolong action potential duration in isolated guinea pig atria [3] and papillary muscle [5], enhance myocardial contractive power and have significant positive inotropic action to both auricular muscle and ventricular muscle [5].…”

Hepatoprotective Effect of <i>Adenema hyssopifolium G. Don</i> (Gentianaceae) in Carbon Tetrachloride-Induced Hepatotoxicity in Rats

“…Furthermore, it has been suggested that iridoid glycoside in certain plants is a critical compound in hepatoprotective activity [20]. The protective activity of aucubin, an iridoid glycoside, against carbon tetrachloride-induced liver damage in mice has been reported [21]. The iridoid glycoside, kutkin, and its glycoside mixtures have also been found to exert hepatoprotective activity.…”