Iridopathy in Eyes with Proliferative Diabetic Retinopathy: Detection of Early Stage of Rubeosis Iridis

Inoue, Masatoshi; Azumi, Atsushi; Shirabe, Hiroko; Yamamoto, Masato

doi:10.1159/000027252

Cited by 10 publications

(11 citation statements)

References 14 publications

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“…However, routine ophthalmoscopy has a low sensitivity for detecting early or subtle stages of IA, a finding confirmed in our study (2 eyes with IA detected clinically, compared with 14 eyes detected histopathologically). 18,28 The degree of AES enhancement might be a valuable diagnostic parameter in the choice between enucleation and conservative treatment strategies. Normal AES enhancement seems to be an indication for considering globe salvage rather than enucleation.…”

Section: Discussionmentioning

confidence: 99%

Contrast-Enhancement of the Anterior Eye Segment in Patients with Retinoblastoma: Correlation between Clinical, MR Imaging, and Histopathologic Findings

Graaf¹,

Valk²,

Moll³

et al. 2009

AJNR Am J Neuroradiol

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Section: Discussionmentioning

confidence: 99%

Contrast-Enhancement of the Anterior Eye Segment in Patients with Retinoblastoma: Correlation between Clinical, MR Imaging, and Histopathologic Findings

Graaf¹,

Valk²,

Moll³

et al. 2009

AJNR Am J Neuroradiol

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“…The DR patients with iris new blood vessels which was not around the pupil margin was excluded to the statistic analysis. The protocol was as follows: (1) The center point of the pupil was marked (Figure 1A). ( 2) The area of leakage lesions around pupil was marked.…”

Section: Iamentioning

confidence: 99%

“…The main complications of diabetic retinopathy were diabetic iridopathy (DI) and diabetic retinopathy (DR) [1]. Iris angiography (IA), which primarily includes iris uorescein angiography (IFA) and iris indocyanine green angiography (IICGA), has been used for the evaluation of DI [2].…”

Section: Introductionmentioning

confidence: 99%

Application of Novel Quantitative Measurement of Iris Angiography in Diabetic Retinopathy

Zhang

Chai

Zhang

et al. 2022

Preprint

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Introduction: The purpose of this study was to explore the application of a novel quantitative measurement of iris angiography (IA) in diabetic retinopathy (DR). Methods: This was a single-center, cross-sectional prospective study. Totally 168 consecutive patients with diabetic mellitus (DM) were involved into this study from May 2016 to December 2020, 168 subjects were devided into 3 groups, 32 non-retinopathy patients,96 non-proliferative diabetic retinopathy patients(NPDR), and 40 proliferative diabetic retinopathy (PDR) patients. All patients underwent ophthalmologic examination, such as best corrected visual acuity, intraocular pressure, slit-lamp microscopy, gonioscopy, ultra-wide-field fundus photography, fluorescein angiography of the iris (IFA), and indocyanine green angiography of the iris (IIGA). The starting of iris vascular leakage time(LT) was recorded, and the range of pupil fluorescein leakage was measured by a novel measurement. Results: LT of iris in non-retinopathy, non-proliferative diabetic retinopathy (NPDR), and proliferative diabetic retinopathy (PDR) groups were 33.14 ± 3.03s, 32.45 ± 5.17s, and 25.67 ± 5.03s, respectively. The LT in the PDR group was significantly faster than those in the NPDR and non-retinopathy groups (P=0.000). The iris pupil leakage range (LR) of the non-retinopathy, NPDR, and PDR groups were 21.21 ± 30.06, 62.48 ± 42.17, and 141.31 ± 73.61°, and LR in PDR groups were largest among all groups (P=0.000). Neovascularization of the iris (NVI) was detected in 8 eyes (26.7%) in the PDR group. No NVI was found in non-retinopathy and NPDR groups.Conclusions: The novel quantitative measurement of IA can be used to evaluate the severity of diabetic iridopathy (DI) accurately and detect invisible NVI as early as possible to provide a basis for the formulation of personalized treatment for DR patients.

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“…The association between diabetic retinopathy and iridopathy is well-known, and iris fluorescein angiography, 8–9 iris indocyanine green angiography, 10 and laser photometry 11 have been used to investigate iris microangiopathy. Iris transillumination may also provide perspective on diabetic iridopathy.…”

Section: Case Reports Observations and Example Applicationsmentioning

confidence: 99%

Novel Observations and Potential Applications Using Digital Infrared Iris Imaging

Roberts¹,

Lukić²,

Yang³

et al. 2009

Ophthalmic Surg Lasers Imaging Retina

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Digital infrared (IR) iris photography using a modified digital camera system was carried out on about 300 subjects seen during routine clinical care and research at one facility. Since this image database offered opportunity to gain new insight into the potential utility of IR iris imaging, it was surveyed for unique image patterns. Then, a selection of photos was compiled that would illustrate the spectrum of this imaging experience. Potentially informative image patterns were observed in subjects with cataracts, diabetic retinopathy, Posner-Schlossman syndrome, iridociliary cysts, long anterior lens zonules, nevi, oculocutaneous albinism, pigment dispersion syndrome, pseudophakia, suspected vascular anomaly, and trauma. Image patterns were often unanticipated regardless of pre-existing information and suggest that IR iris imaging may have numerous potential clinical and research applications, some of which may still not be recognized. These observations suggest further development and study of this technology.

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Iridopathy in Eyes with Proliferative Diabetic Retinopathy: Detection of Early Stage of Rubeosis Iridis

Cited by 10 publications

References 14 publications

Contrast-Enhancement of the Anterior Eye Segment in Patients with Retinoblastoma: Correlation between Clinical, MR Imaging, and Histopathologic Findings

Contrast-Enhancement of the Anterior Eye Segment in Patients with Retinoblastoma: Correlation between Clinical, MR Imaging, and Histopathologic Findings

Application of Novel Quantitative Measurement of Iris Angiography in Diabetic Retinopathy

Novel Observations and Potential Applications Using Digital Infrared Iris Imaging

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