1992
DOI: 10.1016/0098-2997(92)90013-p
|View full text |Cite
|
Sign up to set email alerts
|

Iron chelators in medicine

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1
1
1

Citation Types

0
21
0

Year Published

1994
1994
2022
2022

Publication Types

Select...
8
1

Relationship

0
9

Authors

Journals

citations
Cited by 45 publications
(21 citation statements)
references
References 148 publications
0
21
0
Order By: Relevance
“…Antioxidant therapy has become a successful clinical approach to many of the pathologies that involve free radicals [Hershko, 1992;Barber and Harris, 1994;Tanswell and Freeman, 1995]. Both free radical scavengers and iron chelators may act as antioxidants.…”
Section: Antioxidant Therapymentioning
confidence: 99%
“…Antioxidant therapy has become a successful clinical approach to many of the pathologies that involve free radicals [Hershko, 1992;Barber and Harris, 1994;Tanswell and Freeman, 1995]. Both free radical scavengers and iron chelators may act as antioxidants.…”
Section: Antioxidant Therapymentioning
confidence: 99%
“…Ϫ31 M) and is used to treat iron overload in thalassemia and transfusion patients (14) and has been shown to retard progressive neurological degeneration in Alzheimer's patients (15). In the body, it can remove iron from the C terminus of human skeletal transferrin (16), and E. coli can utilize iron loaded Desferal as an iron source.…”
mentioning
confidence: 99%
“…A subsequent preliminary study from the laboratory of Weinberg and Shaw (46) showed that DFO suppresses the growth of P. carinii in an established cell culture model at concentrations safely achievable in human serum. However, despite the efficacy and safety of DFO as a chelator, its usefulness is limited by the need for parenteral administration, with its associated expense and inconvenience (10,17). …”
mentioning
confidence: 99%