2021
DOI: 10.33549//physiolres.934708
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Is Apelin a new biomarker in patients with polycystic ovary syndrome?

Abstract: Polycystic ovary syndrome (PCOS) is associated with multiple risk factors for cardiovascular diseases, including insulin resistance, diabetes mellitus type 2, obesity, hypertension, and dyslipidaemia. Many studies have assessed the role of adipokines in the etiopathogenesis of PCOS, however, no single biomarker has been recognized to be in causal relation to the syndrome. Apelin has been identified as a new adipokine linked to obesity and insulin resistance. Some studies demonstrated that the apelin / apelin… Show more

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Cited by 2 publications
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“…Apelin is linked to frequent female reproductive pathological conditions such as PCOS, ovarian cancer, and endometriosis ( 14 , 181 , 182 ). In PCOS patients, high levels of apelin in the blood and follicular fluid, and Gc of ovaries were reported ( 22 , 183 ). Roche et al.…”
Section: Apelin and The Hpg Axis And Reproductive Systemmentioning
confidence: 99%
See 1 more Smart Citation
“…Apelin is linked to frequent female reproductive pathological conditions such as PCOS, ovarian cancer, and endometriosis ( 14 , 181 , 182 ). In PCOS patients, high levels of apelin in the blood and follicular fluid, and Gc of ovaries were reported ( 22 , 183 ). Roche et al.…”
Section: Apelin and The Hpg Axis And Reproductive Systemmentioning
confidence: 99%
“…Due to the presence of apelin and its receptor in reproductive-related areas such as the hypothalamus and pituitary gland, its role in controlling the secretion of LH (luteinizing hormone) and FSH (follicle-stimulating hormone) is understandable ( 21 ). Furthermore, apelin is associated with reproductive disorders such as polycystic ovary syndrome (PCOS), endometriosis, and ovarian cancer ( 22 ).…”
Section: Introductionmentioning
confidence: 99%