Is Canada ready for the second wave of COVID-19?

Vogel, Lauren

doi:10.1503/cmaj.1095875

Cited by 15 publications

(14 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Specifically, South Korea has signed an agreement to purchase vaccines for 20 million people from Moderna, 10 million people from AstraZeneca, 6 million from Johnson & Johnson's Janssen, and 10 million from Pfizer. In addition, the country has secured vaccines for 10 million people from the global vaccine supply platform, COVAX Facility [10].…”

Section: Introductionmentioning

confidence: 99%

Optimal Allocation of the Limited COVID-19 Vaccine Supply in South Korea

Shim

2021

JCM

View full text Add to dashboard Cite

Initial supply of the coronavirus disease (COVID-19) vaccine may be limited, necessitating its effective use. Herein, an age-structured model of COVID-19 spread in South Korea is parameterized to understand the epidemiological characteristics of COVID-19. The model determines optimal vaccine allocation for minimizing infections, deaths, and years of life lost while accounting for population factors, such as country-specific age distribution and contact structure, and various levels of vaccine efficacy. A transmission-blocking vaccine should be prioritized in adults aged 20–49 years and those older than 50 years to minimize the cumulative incidence and mortality, respectively. A strategy to minimize years of life lost involves the vaccination of adults aged 40–69 years, reflecting the relatively high case-fatality rates and years of life lost in this age group. An incidence-minimizing vaccination strategy is highly sensitive to vaccine efficacy, and vaccines with lower efficacy should be administered to teenagers and adults aged 50–59 years. Consideration of age-specific contact rates and vaccine efficacy is critical to optimize vaccine allocation. New recommendations for COVID-19 vaccines under consideration by the Korean Centers for Disease Control and Prevention are mainly based on a mortality-minimizing allocation strategy.

show abstract

Section: Introductionmentioning

confidence: 99%

Optimal Allocation of the Limited COVID-19 Vaccine Supply in South Korea

Shim

2021

JCM

View full text Add to dashboard Cite

show abstract

“…The world is sensing an increase of SARS-CoV-2 (Covid-19) contamination with several countries such as France, Spain, and the United Kingdom that are reporting an increasing number of new Covid-19 cases. This increase in cases is due to the second wave of contagion as point some studies like Xu and Li (2020), Cacciapaglia, Cot, andSannino (2020), andVogel (2020).…”

Section: Introductionmentioning

confidence: 71%

Brazilian model estimation for SARS-CoV-2 peak contagion (BMESPC)

Kuroiva²,

Terra

2021

Preprint

View full text Add to dashboard Cite

With newer data for SARS-CoV-2 and entering the second wave of contagion required the improvement of the forecasting model, structuring its model to forecast the peak of the first and second contagion wave in Brazil. The Brazilian model estimation for SARS-CoV-2 peak contagion (BMESPC) was structured, capable of estimating the peak of contagion for SARS-CoV-2 in the first and second waves, as the main objective of this work. Using the BMESPC model, it was possible to estimate, with a certain reliability degree, the peak of contagion for the first and second waves in Brazil, with one day difference from the real to the forecast. While at the state level, the calculated confidence interval proved to be more accurate. In this way, it is possible to use BMESPC to forecast the peak of contagion for several regions, provided that the necessary structure and calibration are respected.

show abstract

“…This is the first reported human subject validation of a locally manufactured reusable respirator using standardized quantitative fit testing (per CSA Z94. [4][5][6][7][8][9][10][11][12][13][14][15][16][17][18]. Within the same collaborative, a 2 nd N95 respirator derivative has been developed that contains valves that prolong filter life, decrease subjective work of breathing, and improve acoustics [14].…”

Section: Discussionmentioning

confidence: 99%

“…A future quality control study question is: "Of those who fail their assigned mask, how many can be retrained to re-pass a 2 nd or 3 rd QNFT on the same respirator and/or another model?" UHN APIL and The Department of Anesthesiology, are in the process of preparing for such a quality-improvement audit, of utmost importance in the 2 nd COVID-19 pandemic wave across Canada [15]. Of particular concern is whether our volunteer facial sizing is comparable to the community, given the average BMI was approximately 24 kg/ m 2 .…”

Section: Discussionmentioning

confidence: 99%

Subject validation of reusable N95 stop-gap filtering facepiece respirators in COVID-19 pandemic

Hondjeu

Syrett

et al. 2020

PLoS ONE

View full text Add to dashboard Cite

Introduction The COVID-19 pandemic has unveiled widespread shortages of personal protective equipment including N95 respirators. Several centers are developing reusable stop-gap respirators as alternatives to disposable N95 respirators during public health emergencies, using techniques such as 3D-printing, silicone moulding and plastic extrusion. Effective sealing of the mask, combined with respiratory filters should achieve 95% or greater filtration of particles less than 1um. Quantitative fit-testing (QNFT) data from these stop-gap devices has not been published to date. Our team developed one such device, the “SSM”, and evaluated it using QNFT. Methods Device prototypes were iteratively evaluated for comfort, breathability and communication, by team members wearing them for 15-30min. The fit and seal were assessed by positive and negative pressure user seal checks. The final design was then formally tested by QNFT, according to CSA standard Z94.4–18 in 40 volunteer healthcare providers. An overall fit-factor >100 is the passing threshold. Volunteers were also tested by QNFT on disposable N95 masks which had passed qualitative fit testing (QLFT) by institutional Occupational Health and Safety Department. Results The SSM scored 3.5/5 and 4/5 for comfort and breathability. The median overall harmonic mean fit-factors of disposable N95 and SSM were 137.9 and 6316.7 respectively. SSM scored significantly higher than disposable respirators in fit-test runs and overall fit-factors (p <0.0001). Overall passing rates in disposable and SSM respirators on QNFT were 65% and 100%. During dynamic runs, passing rates in disposable and SSM respirators were 68.1% and 99.4%; harmonic means were 73.7 and 1643. Conclusions We present the design and validation of a reusable N95 stop-gap filtering facepiece respirator that can match existent commercial respirators. This sets a precedence for adoption of novel stop-gap N95 respirators in emergency situations.

show abstract

Is Canada ready for the second wave of COVID-19?

Cited by 15 publications

References 0 publications

Optimal Allocation of the Limited COVID-19 Vaccine Supply in South Korea

Optimal Allocation of the Limited COVID-19 Vaccine Supply in South Korea

Brazilian model estimation for SARS-CoV-2 peak contagion (BMESPC)

Subject validation of reusable N95 stop-gap filtering facepiece respirators in COVID-19 pandemic

Contact Info

Product

Resources

About