Is erectile dysfunction an early clinical symptom of chronic kidney disease?

Abstract

Objectives: Erectile dysfunction (ED) is the persistent inability to attain and/or maintain erection sufficient for satisfactory sexual performance. Chronic kidney disease (CKD) is a problem with increasing incidence every day which disrupts quality of life significantly. We aimed to research whether ED is a warning symptom for the early stages of CKD or not. Materials and methods: The records of 639 patients attending Ordu University due to ED were retrospectively investigated. According to International Index of Erectile Function (IIEF) scores and degree of ED, patients were compared in terms of GFR values. Results: In 92.8% of patients, serum creatinine values were within normal limits (<1 mg/dL), while 30.5% of patients were observed to have GFR below 80. While stage 2 CKD was identified in 1% of the control group, this rate was calculated as 8% in the group with severe ED. In stage 1 and stage 2 CKD, IIEF scores were identified to be low by clear degree. Conclusions: Results confirm that it was identified that the incidence of stage 1 and stage 2 CKD was higher among patients attending with ED compared to the control group. Just as ED may be an early clinical marker of coronary artery disease, it may be early warning symptom for CKD.

Serum nesfatin‐1 level in men with diabetes and erectile dysfunction correlates with generalized anxiety disorder‐7: A prospective comparative study

“…38 Thus, a recent study highlights the potential utility of ED as an early marker of chronic kidney disease. 39 This finding could be seen in the same context as the present study as it had demonstrated a significant association between IIEF-5 and creatinine. The aforementioned Egyptian study had shown that albuminuria was an independent risk factor of ED which is also similar to our finding.…”

“…There is a strong association between endothelial dysfunction and ED that explains the evolving of systemic diseases in ED 38 . Thus, a recent study highlights the potential utility of ED as an early marker of chronic kidney disease 39 . This finding could be seen in the same context as the present study as it had demonstrated a significant association between IIEF‐5 and creatinine.…”

Efectos del trasplante renal en la función sexual: experiencia en un centro de alta complejidad

“…Cuando se ven afectados estos procesos puede aparecer la disfunción eréctil (DE), definida como la incapacidad constante o recuente para lograr o mantener una erección del pene suficiente para la satisfacción, incluido el desempeño sexual satisfactorio 3 . Se estima una incidencia global de 25 a 30 casos nuevos por cada 1000 personas 4 . La DE es multifactorial, asociada a comorbilidad como la hipertensión arterial, las cardiopatías, la diabetes, la obesidad, la dislipidemia y la arterioesclerosis, entre otras [2][3][4] .…”

“…Se estima una incidencia global de 25 a 30 casos nuevos por cada 1000 personas 4 . La DE es multifactorial, asociada a comorbilidad como la hipertensión arterial, las cardiopatías, la diabetes, la obesidad, la dislipidemia y la arterioesclerosis, entre otras [2][3][4] . La enfermedad renal crónica (ERC) es una causa importante de DE, siendo explicada por el deterioro endotelial, y en los pacientes con manifestación clínica de DE es un marcador temprano de ERC 4 .…”

Does chronic kidney disease affect the complications and prognosis of patients after primary colorectal cancer surgery?

“…It is estimated that approximately 500 million adults worldwide are diagnosed with chronic kidney disease (CKD), but the prevalence varies greatly among different countries[ 9 , 10 ]. CKD can increase mortality and morbidity, and it involves an economic burden as well[ 11 , 12 ]. Some key pathophysiological causes of CKD may contribute to increased postoperative morbidity (including excessive arterial calcification, endothelial dysfunction and increased levels of inflammatory factors)[ 13 ].…”