2001
DOI: 10.1007/s004640080207
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Is frozen section effective for diagnosis of unsuspected gallbladder cancer during laparoscopic cholecystectomy?

Abstract: Frozen section is effective in cases with T2 or greater lesions for which conversion to radical surgery should be required.

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Cited by 40 publications
(35 citation statements)
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“…Therefore, frozen section examination of suspected lesions should be performed during LC [3]. Aoki et al [14] reported that frozen section during LC was performed in 990 patients with gallstones, and 983 cases were diagnosed as benign and 7 cases as malignant. However, of the benign cases, cancer was discovered postoperatively in four patients whose frozen sections had indicated regenerative epithelial severe atypia (sensitivity 64%).…”
Section: Discussionmentioning
confidence: 99%
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“…Therefore, frozen section examination of suspected lesions should be performed during LC [3]. Aoki et al [14] reported that frozen section during LC was performed in 990 patients with gallstones, and 983 cases were diagnosed as benign and 7 cases as malignant. However, of the benign cases, cancer was discovered postoperatively in four patients whose frozen sections had indicated regenerative epithelial severe atypia (sensitivity 64%).…”
Section: Discussionmentioning
confidence: 99%
“…In gallbladders that are full of gallstones, mucosal changes are impossible to detect using ultrasound (US) examination, and the diagnosis of small carcinomas remains unreliable using either US or CT. Moreover, the flat type of GBC is difficult to detect macroscopically, and sclerotic mucosa and thickening of one part of the gallbladder wall has been detected in almost all patients with cholecystolithiasis or chronic cholecystitis, which can confound the diagnosis [14]. Therefore, frozen section examination of suspected lesions should be performed during LC [3].…”
Section: Discussionmentioning
confidence: 99%
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“…The accuracy of diagnosis of EGC varies from 80% to 85% in the literature [1,3]. This suggests the high degree of accuracy of microscopic diagnosis [10]. On the other hand, Albores-Saavedra and colleagues [11,12] have reported that EGC could not be identified microscopically, and that the images could not be distinguished from chronic cholecystitis.…”
Section: Discussionmentioning
confidence: 93%